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Optimal Treatment Frequency of 308-Nm Excimer Laser for Vitiligo on the Face and Neck

Sponsor
Air Force Military Medical University, China (Other)
Overall Status
Completed
CT.gov ID
NCT00368407
Collaborator
(none)
1
Location
15
Duration (Months)

Study Details

Study Description

Brief Summary

To determine the optimal treatment frequency of 308-nm excimer laser for vitiligo and identify the key clinical variable(s) associated with the treatment efficiency under the optimal treatment frequency.

Prospective, randomized, comparative study among groups of vitiligo patients treated with 308-nm excimer laser, with the limitation of no follow-up.

Condition or Disease Intervention/Treatment Phase
  • Device: 308-nm excimer laser

Detailed Description

Vitiligo patients were treated with 308-nm excimer laser for 20 sessions at different frequencies (0.5×, 1.0×, 2.0× and 3.0× weekly). Treatment protocols adapted the dose to the lesions and not to the minimal erythemal dose. Treatment efficacy was blindly evaluated by 2 independent physicians. Re-pigmentation rate was graded on a 6-point scale. The onset of re-pigmentation of vitiligo lesions was evaluated after 5 treatment sessions. The differences between Group 0.5×, 1.0×, 2.0× and 3.0× linking different clinical variables were assessed.

Study Design

Study Type:
Observational
Time Perspective:
Prospective
Official Title:
Optimal Treatment Frequency of 308-Nm Excimer Laser for Vitiligo on the Face and Neck
Study Start Date :
Apr 1, 2005
Study Completion Date :
Jul 1, 2006

Outcome Measures

Primary Outcome Measures

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    2 Years to 60 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    • older than 2 years, stable vitiliginous patches during the past 3 months with surfaces of at least 4cm2, and an understanding of all information given by signing a written consent form.
    Exclusion Criteria:
    • pregnant or breastfeeding women; personal history of a hypertrophic scar, skin cancer; taking immunosuppressive or photosensitizing drugs and undergoing phototherapy during the past 3 months.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Department of dermatology, Xijing Hospital Xi'an SHANNXI China 710032

    Sponsors and Collaborators

    • Air Force Military Medical University, China

    Investigators

    • Study Director: gao tianwen, MD,PHD, Ddepartment of Dermatology

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00368407
    Other Study ID Numbers:
    • fmmu200504
    First Posted:
    Aug 24, 2006
    Last Update Posted:
    Aug 24, 2006
    Last Verified:
    Apr 1, 2005
    Keywords provided by , ,
    308-nm excimer laser
    vitiligo
    Additional relevant MeSH terms:
    Vitiligo

    Study Results

    No Results Posted as of Aug 24, 2006