HEMOBOX: Optimal Hemostasis Duration for Percutaneous Coronary Intervention Via Snuffbox Approach
Study Details
Study Description
Brief Summary
Transradial approach has been preferred for coronary angiography (CAG) and percutaneous coronary intervention (PCI) due to several advantages, including decreased associated vascular complication, patients' convenience, and early ambulation compared with transfemoral approach. With these advantages, current guidelines support that radial access is recommended for CAG and PCI in acute myocardial infarction (AMI) patients with and without ST-elevation if performed by an experienced radial operator. Recently, Kiemeneij introduced a distal radial artery approach, called the snuffbox approach, and several studies have been published. However, the feasibility of PCI via snuffbox approach is still concerned due to the lack of data. Moreover, optimal hemostasis duration for PCI via snuffbox approach has not been investigated, even though shorter hemostasis duration would be expected compared with the conventional radial approach as diameter of snuffbox radial artery was significantly smaller than conventional radial artery. In addition, there are few data regarding the feasibility of PCI via snuffbox approach. Therefore, the aim of the study is to evaluate the optimal hemostasis duration for PCI via snuffbox approach.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Snuffboxer Patients undergoing percutaneous coronary intervention via snuffbox approach |
Procedure: Percutaneous coronary intervention via snuffbox approach
After local anesthesia on left or right anatomical snuffbox with lidocaine hydrochloride using a 26 gauge needle, the puncture is performed using a 20 gauge needle with the through-and-through puncture technique or a 21 gauge open needle with anterior wall puncture technique. After successful puncture, 0.025-inch straight wire or 0.018-inch hair wire are inserted, followed by an insertion of the 5Fr. or 6Fr radial sheath (Prelude® Radial; Merit medical, UT, USA or Radifocus® Introducer II or Glidesheath Slender®; Terumo Corporation, Tokyo, Japan). The selection of puncture device is at physician discretion.
|
Outcome Measures
Primary Outcome Measures
- Hemostasis duration (minute) [1 year]
Hemostasis is obtained by compressive bandage with 3 modified gauzes using cohesive elastic bandage (Peha-Haft®, HARTMANN Inc, SC, USA).
Secondary Outcome Measures
- Correlation between activated clotting time (ACT) and hemostasis duration [1 year]
- Success rate of PCI via snuffbox approach (%) [1 year]
The frequency of success rate of percutaneous coronary intervention via snuffbox approach
- Puncture site complication after hemostasis [1 year]
Evaluation of puncture-site bleeding complication using EASY criteria
- Snuffbox cannulation time (second) [1 year]
Time from local anesthesia to sheath cannulation
- Success rate of snuffbox approach (%) [1 year]
Successful introduction of sheath
Eligibility Criteria
Criteria
Inclusion Criteria:
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Patients ≥18 years old requiring PCI
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Patients who are palpable distal radial arter
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The decision to participate voluntarily in this study and the written consent of the patient
Exclusion Criteria:
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Patients who are not palpable distal radial artery
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Female of childbearing potential, who possibly plans to become pregnant any time after enrollment into this study.
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Patients who are not appropriate for this study
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Chonnam National University Hospital | Gwangju | Korea, Republic of | 61469 |
Sponsors and Collaborators
- Chonnam National University Hospital
- Wakayama Medical University
- The Catholic University of Korea
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- HEMOBOX