Oral Findings In A Group of Egyptian Children With Attention Deficit Hyperactivity Disorder

Sponsor

Cairo University (Other)

Overall Status

Unknown status

CT.gov ID

NCT03887039

Collaborator

(none)

Enrollment

Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

Attention-deficit/hyperactivity disorder is the most common childhood neuro-developmental disorder that is characterized by inattention, hyperactivity, and impulsivity. These symptoms last till adulthood in 65% of cases. ADHD has been reported to have a worldwide prevalence of 5.3% and it is more common in boys than in girls (Ghanizadeh 2008; Serra-Negra et al. 2012 and Shooshtari et al. 2013) The symptoms of ADHD are generally treated through behavioral therapy, with or without pharmacological intervention. Medications prescribed are commonly divided into stimulant or non-stimulant drugs. The stimulant medications (such as methylphenidate and amphetamines) have been implicated in adverse oral effects, such as xerostomia and gingival enlargement. The current evidence is controversial regarding the severity and prevalence of dental caries, dental trauma, periodontal diseases, oral habits and tooth wear among patients with ADHD (Chau et al. 2017).

In the Arab world, few studies have been published on ADHD. Accordingly, in the Arab society and Egypt there are limited data regarding the oral findings of children with ADHD. Owing to the sparsity of these data, this study will be conducted to evaluate different oral characteristics of Egyptian children with ADHD.

Condition or Disease	Intervention/Treatment	Phase
Oral Manifestations	Other: clinical examination

Detailed Description

Due to lack of published studies about the oral findings of Egyptian Children with ADHD, this study will be conducted to cover this point.

Study Design

Study Type:

Observational

Anticipated Enrollment :

78 participants

Observational Model:

Other

Time Perspective:

Cross-Sectional

Official Title:

Oral Findings In A Group of Egyptian Children With Attention Deficit Hyperactivity Disorder: A Cross-Sectional Study

Anticipated Study Start Date :

Aug 1, 2019

Anticipated Primary Completion Date :

Jun 1, 2020

Anticipated Study Completion Date :

Jul 1, 2020

Arms and Interventions

Arm	Intervention/Treatment
ADHD group clinical examination	Other: clinical examination clinical examination for all the oral findings
normal group clinical examination	Other: clinical examination clinical examination for all the oral findings

Arm

Intervention/Treatment

ADHD group

clinical examination

Other: clinical examination

clinical examination for all the oral findings

normal group

clinical examination

Other: clinical examination

clinical examination for all the oral findings

Outcome Measures

Primary Outcome Measures

oral habits [6 months]
clinical examination yes/no

Secondary Outcome Measures

DMFT caries index [6 months]
DMFT D=dacayed M=missed due to caries F=filled T=tooth score 0-20 for primary teeth0 is the best / 20 is the worst
dental trauma [6 months]
clinical examination yes/no

Eligibility Criteria

Criteria

Ages Eligible for Study:

3 Years to 6 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

- Egyptian children 3-6 years old diagnosed with ADHD.
Patients taking medications for the treatment of ADHD or not.
Both male and female patients will be included.

Control Group:

A matched group of healthy children aged 3-6 years old.

Exclusion Criteria:

- Non-Egyptian children.
Patients having systemic disorders, such as cerebral palsy or Down's syndrome.
Patients complaining from any systemic disease

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Cairo University

Investigators

Principal Investigator: Sara G Hussien, BSc, Resident at pediatric Dentistry and Dental Public Health Department
Study Director: Randa Y Abdel Gawad, PhD, Associate professor at pediatric Dentistry and Dental Public Health Department