Water and the Gastropressor Response - Diurnal Variability

• Sponsor: Satish R. Raj (Other)
• Overall Status: Active, not recruiting
• CT.gov ID: NCT00581373
• Collaborator: (none)
• Enrollment: 20
• Location: 1
• Arm: 1
• Duration (Months): 220
• Patients Per Site Per Month: 0.1

Study Details

Study Description

Brief Summary

We will test the null hypothesis that there is no diurnal (morning to afternoon)variability in the blood pressure response to the ingestion of water 16 oz.

Condition or Disease	Intervention/Treatment	Phase
Orthostatic Hypotension	Other: water 16 fl oz	N/A

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 20 participants
• Allocation: N/A
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: Water and the Gastropressor Response - Diurnal Variability (Specific Aim 1.3)
• Study Start Date: Aug 1, 2007
• Anticipated Primary Completion Date: Dec 1, 2025
• Anticipated Study Completion Date: Dec 1, 2025

Arms and Interventions

Arm	Intervention/Treatment
Experimental: 1 water 16 oz	Other: water 16 fl oz; water 16 fl oz in AM and repeat in late afternoon

Outcome Measures

Primary Outcome Measures

1. blood pressure [1 day]

Secondary Outcome Measures

1. heart rate [1 day]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 80 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• orthostatic intolerance

Exclusion Criteria:

• pregnancy

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Vanderbilt University	Nashville	Tennessee	United States	37232

Sponsors and Collaborators

• Satish R. Raj

Investigators

• Principal Investigator: Satish R Raj, MD MSCI, Vanderbilt University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Satish R. Raj, Assistant Professor of Medicine & Pharmacology, Vanderbilt University Medical Center
• ClinicalTrials.gov Identifier: NCT00581373
• Other Study ID Numbers: 060553; Vanderbilt Discovery
• First Posted: Dec 27, 2007
• Last Update Posted: Sep 8, 2021
• Last Verified: Sep 1, 2021

• Keywords provided by Satish R. Raj, Assistant Professor of Medicine & Pharmacology, Vanderbilt University Medical Center: water; orthostatic hypotension; blood pressure
• Additional relevant MeSH terms: Hypotension, Orthostatic; Hypotension

Study Results

No Results Posted as of Sep 8, 2021