NSAID Treatment of Patients With Osteoarthritis

• Sponsor: Aalborg University (Other)
• Overall Status: Completed
• CT.gov ID: NCT02967744
• Collaborator: (none)
• Enrollment: 162
• Location: 1
• Arm: 1
• Duration (Months): 25
• Patients Per Site Per Month: 6.5

Study Details

Study Description

Brief Summary

The study investigates associations between pre treatment pain intensity and central pain mechanisms on the effect of 8-week treatment of NSAIDs in patients with knee osteoarthritis.

Condition or Disease	Intervention/Treatment	Phase
Osteoarthritis,Knee	Drug: NSAID	N/A

Study Design

• Study Type: Interventional
• Actual Enrollment: 162 participants
• Allocation: N/A
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Primary Purpose: Diagnostic
• Official Title: BEVAR: Patientspecifik Behandling Ved Artrose - Et "Proof-of-concept"- Kvalitetssikringsstudie
• Study Start Date: Jan 1, 2016
• Actual Primary Completion Date: Jan 1, 2018
• Actual Study Completion Date: Feb 1, 2018

Arms and Interventions

Arm	Intervention/Treatment
Experimental: NSAID treatment 8 weeks of NSAID treatment	Drug: NSAID; NSAIDs are among the most common pain treatments for patients with osteoarthritis.

Outcome Measures

Primary Outcome Measures

1. Pain intensity measured on a 10cm visual analog scale [8 weeks after treatment]

   Patients will be asked to rate the pain intensity 8 weeks after treatment on a 10cm visual analog scale (0 indicating no pain, 10 indicating worst imaginable pain

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 80 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Diagnosed Knee Ostoarthritis

Exclusion Criteria:

• Current ulcer diagnosed by endoscope

• Asthma or other allergic reaction to NSIADs

• Kidney disease

• Myocardial infarction within the last six months

• Severe hyper tension (systolic ≥180mmHg, diastolic ≥110mmHg)

• Severe thrombocytopenia (thrombocyst count <50x10^9/l)

• Insufficience lever or kidney function

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Center for Sensory Motor Interaction, Aalborg University	Aalborg East		Denmark	9220

Sponsors and Collaborators

• Aalborg University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Kristian Kjær Petersen, assistant professor, Aalborg University
• ClinicalTrials.gov Identifier: NCT02967744
• Other Study ID Numbers: N-20140077
• First Posted: Nov 18, 2016
• Last Update Posted: Mar 27, 2018
• Last Verified: Mar 1, 2018

• Additional relevant MeSH terms: Osteoarthritis; Osteoarthritis, Knee

Study Results

No Results Posted as of Mar 27, 2018