Determination of Adipocyte Parameters in Iliac Crest Biopsies From Post Menopausal Women
Sponsor
Mayo Clinic (Other)
Overall Status
Completed
CT.gov ID
NCT00443716
Collaborator
(none)
60
1
48
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Study Details
Study Description
Brief Summary
To evaluate the effect of estrogen treatment on adipocytic and osteoblastic parameters by histomorphometrically measuring adipocyte volume (AV/TV) and adipocyte numbers in goldner's stained iliac crest bone biopsy specimens collected from subjects recruited in the study (IRB number 21B85). The adipocytic parameters will be then correlated with osteoblastic parameters obtained previously during the course of the initai study involving the effect of transdermal estrogen on bone turnover in postmenopausal osteoporotic women.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
N/A |
Study Design
Study Type:
Interventional
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Determination of Adipocyte Parameters in Iliac Crest Biopsies From Post Menopausal Women
Study Start Date
:
Apr 1, 1985
Actual Primary Completion Date
:
Apr 1, 1989
Actual Study Completion Date
:
Apr 1, 1989
Outcome Measures
Primary Outcome Measures
- efficacy of estraderm treatment on osteoporotic women []
Eligibility Criteria
Criteria
Ages Eligible for Study:
30 Years
and Older
Sexes Eligible for Study:
Female
Accepts Healthy Volunteers:
Yes
Post-menopausal osteoporotic women
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Mayo Clinic | Rochester | Minnesota | United States | 55905 |
Sponsors and Collaborators
- Mayo Clinic
Investigators
- Principal Investigator: B. Lawrence Riggs, M.D., Mayo Clinic
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT00443716
Other Study ID Numbers:
- 05-004111
- 21b85
First Posted:
Mar 6, 2007
Last Update Posted:
Jan 15, 2010
Last Verified:
Jan 1, 2010