Treatment in Right Colon Diverticulitis Patients

• Sponsor: Tepecik Training and Research Hospital (Other)
• Overall Status: Completed
• CT.gov ID: NCT04746326
• Collaborator: (none)
• Enrollment: 26
• Location: 1
• Arms: 2
• Actual Duration (Months): 12.6
• Patients Per Site Per Month: 2.1

Study Details

Study Description

Brief Summary

The right colon diverticula, unlike those in the left colon, contain all layers of the colon and is called the true diverticulum. Perforation is observed less frequently due to its full thickness. Conservative treatment can be applied unless complications such as abscess formation and free perforation occur. Unlike the left, right colon diverticulitis has low complications and can be treated conservatively. The differential diagnosis of right colon diverticulitis should be kept in mind in order to prevent unnecessary surgeries. Surgical treatment is inevitable in cases such as recurrent diverticulitis, generalized peritonitis, and suspected malignancy.

Condition or Disease	Intervention/Treatment	Phase
Outcome	Procedure: Failure conservative treatment; Procedure: Surgery; Other: Conservative treatment	N/A

Detailed Description

The right colon diverticula, unlike those in the left colon, contain all layers of the colon and is called the true diverticulum. Perforation is observed less frequently due to its full thickness. Conservative treatment can be applied unless complications such as abscess formation and free perforation occur. Here, we aimed to discuss the results of conservative and surgical treatment for right colon diverticulitis in the light of the literature. 150 patients treated for colon diverticulitis between 2015-2020 were retrospectively screened. Right colon diverticulitis detected incidentally, missing data, and left colon diverticulitis were excluded from the study. Data of a total of 26 patients were accessed. Unlike the left, right colon diverticulitis has low complications and can be treated conservatively. The differential diagnosis of right colon diverticulitis should be kept in mind in order to prevent unnecessary surgeries. Surgical treatment is inevitable in cases such as recurrent diverticulitis, generalized peritonitis, and suspected malignancy

Study Design

• Study Type: Interventional
• Actual Enrollment: 26 participants
• Allocation: Non-Randomized
• Intervention Model: Parallel Assignment
• Intervention Model Description: Conservative treatment, Operative treatmentConservative treatment, Operative treatment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: Operative and Conservative Treatment in Right Colon Diverticulitis Patients
• Actual Study Start Date: Jan 1, 2020
• Actual Primary Completion Date: Jan 1, 2021
• Actual Study Completion Date: Jan 20, 2021

Arms and Interventions

Arm	Intervention/Treatment
Other: Conservative treatment Conservative treatment stopping oral intake, intravenous antibiotic therapy.	Other: Conservative treatment; Conservative treatment was performed in patients who had no generalized peritonitis and perforation.
Other: Operative treatment Operative procedure Right hemicolectomy Wedge resection of cecum Diverticulectomy + appendectomy Diverticulectomy Appendectomy + drainage	Procedure: Failure conservative treatment; Surgery was performed in patients who failed conservative treatment.; Procedure: Surgery; Surgery was performed in patients who had generalized peritonitis and perforation.

Outcome Measures

Primary Outcome Measures

1. Number of Participants with mortality [up to 24 weeks]

   mortality

2. Number of Participants with wound infection [up to 24 weeks]

   wound infection

Eligibility Criteria

Criteria

• Ages Eligible for Study: N/A and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• diagnosed with right colon diverticulitis

Exclusion Criteria:

• Left colon diverticulitis

• Right colon diverticulitis detected incidentally

• lacking data

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Tepecik Training and Research Hospital	İzmir		Turkey	35180

Sponsors and Collaborators

• Tepecik Training and Research Hospital

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Semra Demirli Atici, Primary investigator, Tepecik Training and Research Hospital
• ClinicalTrials.gov Identifier: NCT04746326
• Other Study ID Numbers: 2020 / 14-6
• First Posted: Feb 9, 2021
• Last Update Posted: Feb 9, 2021
• Last Verified: Feb 1, 2021

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by Semra Demirli Atici, Primary investigator, Tepecik Training and Research Hospital: diverticulum; surgery; appendicitis; sigmoid volvulus; caecum; diverticulitis
• Additional relevant MeSH terms: Diverticulitis; Diverticulitis, Colonic

Study Results

No Results Posted as of Feb 9, 2021