Dehydroepiandrosterone Supplementation for Poor Responder Patients During in Vitro Fertilization Treatment

Sponsor

Meir Medical Center (Other)

Overall Status

Completed

CT.gov ID

NCT01145144

Collaborator

(none)

Locations

Arms

Duration (Months)

Study Details

Study Description

Brief Summary

The aim of this study was to evaluate the effect of dehydroepiandrosterone supplementation on in vitro fertilization performance and outcome among poor-responder patient.

Condition or Disease	Intervention/Treatment	Phase
Ovarian Stimulation	Drug: dehydroepiandrosterone crystalline fine powder	N/A

Study Design

Study Type:

Interventional

Allocation:

Randomized

Intervention Model:

Single Group Assignment

Masking:

None (Open Label)

Primary Purpose:

Treatment

Study Start Date :

Jan 1, 2008

Actual Primary Completion Date :

Jul 1, 2009

Actual Study Completion Date :

Jul 1, 2009

Arms and Interventions

Arm	Intervention/Treatment
Experimental: DHEA supplementation DHEA was added to induction of ovulation by recombinant FSH and recombinant LH, in IVF long protocol	Drug: dehydroepiandrosterone crystalline fine powder
No Intervention: only induction of ovulation by same long protocol without DHEA

Arm

Intervention/Treatment

Experimental: DHEA supplementation

DHEA was added to induction of ovulation by recombinant FSH and recombinant LH, in IVF long protocol

Drug: dehydroepiandrosterone crystalline fine powder

No Intervention: only induction of ovulation by same long protocol without DHEA

Outcome Measures

Primary Outcome Measures

peak estradiol level. []
number of retrieved oocytes. []
Embryos that were graded as a top quality (according to the number of cells and percent of fragmentation) []
number of embryos reserved for transfer. []