Clincosm LogoSign in Get a demo

Muffin: Effects of Medium Chain Triglyceride Oil, Versus Olive Oil, for Weight Loss

Sponsor
University of Alabama at Birmingham (Other)
Overall Status
Completed
CT.gov ID
NCT00529919
Collaborator
International Life Sciences Institute (Other)
53
Enrollment
1
Location
2
Arms
27
Duration (Months)
2
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The primary aim of this research project is to determine whether the incorporation of food products containing medium chain triglyceride (MCT) oil in a weight-loss program results in a different degree of weight-loss and total and regional fat mass loss than the incorporation of extra light olive oil. The secondary goals are to test whether there are differences in in metabolic risk profile changes between the 2 diets. We hypothesize that men and women who consumed MCT oil as part of their weight loss program will lose more weight and body fat than those who consume olive oil in their weight loss diet.

Condition or Disease Intervention/Treatment Phase
  • Dietary Supplement: Weight loss
 N/A

Study Design

Study Type:
Interventional
Actual Enrollment :
53 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Double (Participant, Care Provider)
Primary Purpose:
Treatment
Official Title:
The Effects of a Weight Loss Diet Containing Medium Chain Triglyceride Oil, Versus Olive Oil, on Body Composition in Free-Living Adults
Study Start Date :
Mar 1, 2005
Actual Study Completion Date :
Jun 1, 2007

Arms and Interventions

Arm Intervention/Treatment
Active Comparator: 1

MCT oil consumption

Dietary Supplement: Weight loss
Weight loss study including consumption of either 22-25 g of medium chain triglyceride oil or olive oil
Other Names:
  • MCT oil, Neobee 1053, Stepan Company

    		•
    Placebo Comparator: 2

    Olive oil consumption

    Dietary Supplement: Weight loss
    Weight loss study including consumption of either 22-25 g of medium chain triglyceride oil or olive oil
    Other Names:
  • MCT oil, Neobee 1053, Stepan Company

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Change in body weight and fat mass, change in plasma lipid concentrations, fasting glucose and fasting insulin [16 weeks]

    Secondary Outcome Measures

    1. Change in blood pressure, change in fat-free mass [16 weeks]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    19 Years to 50 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • body mass index 27-33 kg/m2

    • pre-menopausal women

    • weight stable for at least 6 months

    • normal score on Brief Symptoms Inventory questionnaire

    Exclusion Criteria:

    • chronic disease

    • weight loss treatment

    • medication known to affect body weight

    • unstable blood pressure, glucose, lipid levels

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 University of Alabama at Birmingham Birmingham Alabama United States 35294

    Sponsors and Collaborators

    • University of Alabama at Birmingham
    • International Life Sciences Institute

    Investigators

    • Principal Investigator: Marie-Pierre St-Onge, Ph.D, St. Luke's-Roosevelt Hospital Center

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00529919
    Other Study ID Numbers:
    • F050124003
    First Posted:
    Sep 14, 2007
    Last Update Posted:
    Sep 14, 2007
    Last Verified:
    Sep 1, 2007
    Keywords provided by , ,
    Overweight
    Obesity
    Weight loss
    Medium chain triglycerides
    Cardiovascular disease risk
    Additional relevant MeSH terms:
    Overweight
    Weight Loss

    Study Results

    No Results Posted as of Sep 14, 2007