Impact of Eating Beans on Metabolism

Sponsor
USDA Grand Forks Human Nutrition Research Center (U.S. Fed)
Overall Status
Recruiting
CT.gov ID
NCT06123208
Collaborator
(none)
28
1
3
24.1
1.2

Study Details

Study Description

Brief Summary

The purpose of this research is to test how eating a meal containing beans impacts how participants' bodies use food for energy.

Condition or Disease Intervention/Treatment Phase
  • Other: Whole cooked pinto bean
  • Other: Pinto bean flour
  • Other: Control
N/A

Detailed Description

The objective of this project is to test whether consuming a whole food that naturally contains resistant starch (RS), such as pulses, increases fat oxidation. The primary hypothesis is that consuming a RS-rich meal in which the RS is derived from a whole food (i.e., pinto beans, pinto bean flour) will increase postprandial fat oxidation to a greater extent than consuming a meal low in RS but containing the same amount of energy and macronutrient content.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
28 participants
Allocation:
Randomized
Intervention Model:
Crossover Assignment
Masking:
None (Open Label)
Primary Purpose:
Other
Official Title:
The Influence of the Resistant Starch and Protein Content of Pulses on Substrate Oxidation
Actual Study Start Date :
Oct 30, 2023
Anticipated Primary Completion Date :
Nov 1, 2025
Anticipated Study Completion Date :
Nov 1, 2025

Arms and Interventions

Arm Intervention/Treatment
Experimental: Whole cooked pinto bean meal

Participants will consume a meal comprised of 100 grams of whole cooked pinto beans

Other: Whole cooked pinto bean
Meal comprised of whole cooked pinto beans

Experimental: Pinto bean flour meal

Participants will consume a meal comprised of pinto bean flour equivalent to 100 grams of whole cooked pinto beans

Other: Pinto bean flour
Meal comprised of pinto bean flour

Active Comparator: Control meal

Participants will consume a control meal

Other: Control
Control meal

Outcome Measures

Primary Outcome Measures

  1. Fat, carbohydrate, and protein utilization [5 hours after meal consumption]

    The effect of consuming whole beans or bean-derived flour on the use of fat, carbohydrate, and protein for energy.

Eligibility Criteria

Criteria

Ages Eligible for Study:
19 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • BMI >18.5 or <30 kg/m2

  • Ability to understand and sign the consent form

  • Ability of transportation (i.e., participants must be able to provide their own transportation to the Grand Forks Human Nutrition Research Center)

  • Non-smoking or use of other tobacco products, including e-cigarettes

  • Not taking steroid-based medications; not planning to or currently attempting to gain or lose weight

  • All females of childbearing age must be on birth control for a minimum of 3 months prior to start of study

Exclusion Criteria:
  • Inability or unwillingness to consume any food item in the test meals

  • More than a 10% change in body weight within the past 2 months

  • Participation in a weight loss diet/exercise program

  • Current or planned pregnancy

  • Lactation

  • Uncontrolled hypertension (systolic >160 mmHg or diastolic >100 mmHg)

  • Diagnosed cardiovascular, pulmonary, skeletal and metabolic diseases

  • Fasting glucose > 100 mg/dL or non-fasting (1-2 hours after eating) >140 mg/dL

  • Using medications known to affect appetite, blood lipids, body composition, body weight, or food intake (appetite control drugs, steroids, antidepressants)

  • Non-English speaking

Contacts and Locations

Locations

Site City State Country Postal Code
1 USDA Grand Forks Human Nutrition Research Center Grand Forks North Dakota United States 58203

Sponsors and Collaborators

  • USDA Grand Forks Human Nutrition Research Center

Investigators

  • Principal Investigator: Shanon Casperson, PhD, USDA Grand Forks Human Nutrition Research Center

Study Documents (Full-Text)

None provided.

More Information

Additional Information:

Publications

None provided.
Responsible Party:
Shanon Casperson, Research Biologist, USDA Grand Forks Human Nutrition Research Center
ClinicalTrials.gov Identifier:
NCT06123208
Other Study ID Numbers:
  • GFHNRC513
First Posted:
Nov 8, 2023
Last Update Posted:
Nov 8, 2023
Last Verified:
Nov 1, 2023
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Nov 8, 2023