Effectiveness of Pain Control and Adverse Reactions After Intravenous PCA in Chinese Population

Sponsor
Huazhong University of Science and Technology (Other)
Overall Status
Completed
CT.gov ID
NCT05884021
Collaborator
(none)
40,000
84

Study Details

Study Description

Brief Summary

Here, we retrospectively analyzed the proportion of intravenous patient controlled analgesia (PCA) used in a large tertiary hospital in central China, and then further analyzed the proportion of patients with postoperative pain after standardized pain treatment and the incidence of adverse effects. It aims to answer are:

  1. The incidence of poor postoperative analgesia and adverse effects of patients with different types of surgery after standardized postoperative pain management of TJ-APS team;

  2. It would provide reference for improving the quality of postoperative acute pain management. In addition, it supplements the Chinese data on the incidence of poor postoperative analgesia and adverse effects of patients under the APS standardized postoperative analgesia process.

Condition or Disease Intervention/Treatment Phase
  • Other: Postoperative analgesia

Detailed Description

Acute pain service (APS) is an important management mode to improve postoperative acute pain, and it has been widely used in hospitals around the world for many years. According to a survey, more than 60% of hospitals in Europe and America have APS teams. Most of the information on postoperative pain management is mainly based on the research performed in United States, Germany and other European countries. Moreover, the current clinical research on postoperative analgesia is mainly focused on improving analgesia technology and drugs, while there are few studies on the impact of postoperative pain management (such as APS) on the prognosis of patients, especially the research on large samples. Considering that China's population accounts for about 21.5% of the world's population, the United States accounts for about 4.3% of the world's population, and Germany accounts for about 1%. Therefore, it is necessary to study the current situation of analgesia in China, especially the poor postoperative analgesia and adverse effects after different types of surgery in Chinese patients. The 27th National Anesthesia Academic Annual Meeting in 2019 reported that only 25.12% of hospitals in China have established APS or similar groups, and only 23.48% provided pain treatment education before surgery, and less than 10% of them are responsible for the whole process of postoperative analgesia services.

Study Design

Study Type:
Observational
Actual Enrollment :
40000 participants
Observational Model:
Cohort
Time Perspective:
Retrospective
Official Title:
Effectiveness of Pain Control and Adverse Reactions After Intravenous PCA in Chinese Population
Actual Study Start Date :
Jan 1, 2016
Actual Primary Completion Date :
Dec 31, 2021
Actual Study Completion Date :
Dec 31, 2022

Outcome Measures

Primary Outcome Measures

  1. Poor postoperative analgesia [2016-2021]

    Incidence of poor postoperative analgesia

Secondary Outcome Measures

  1. Incidence of adverse effects of postoperative analgesia [2016-2021]

    Incidence of adverse effects of postoperative analgesia, especially postoperative nausea and vomiting

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • The surgical patients in Tongji Hospital (Central Operating Room of Hankou Hospital) affiliated to Tongji Medical College of Huazhong University of Science and Technology from January 2016 to December 2021
Exclusion Criteria:
  • Some cases with incomplete patient information records and incomplete patient follow-up data records due to human factors were excluded.

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Huazhong University of Science and Technology

Investigators

  • Principal Investigator: Xianwei Zhang, Doctor, Huazhong University of Science and Technology

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
Xianwei Zhang,MD, Clinical Professor, Huazhong University of Science and Technology
ClinicalTrials.gov Identifier:
NCT05884021
Other Study ID Numbers:
  • postoperative pain
First Posted:
Jun 1, 2023
Last Update Posted:
Jun 1, 2023
Last Verified:
May 1, 2023
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Xianwei Zhang,MD, Clinical Professor, Huazhong University of Science and Technology
Additional relevant MeSH terms:

Study Results

No Results Posted as of Jun 1, 2023