Erector Spinae Plane Block in Liver Transplantation Donors
Study Details
Study Description
Brief Summary
Living donor liver transplantation has become a common treatment option for patients with end-stage liver disease. Donor hepatectomy is associated with significant postoperative pain due to inverted L-shaped incision. Therefore adequate analgesia is important for recovery.
Erector Spinae Plane Block (ESPB) is a safe anesthesia technique used to provide postoperative analgesia. This study aimed to compare the novel ultrasound-guided ESPB technique with controls in terms of postoperative opioid consumption and postoperative pain control on donor patients.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: Erector Spinae Plane Block Erector Spinae Plane Block for Postoperative Analgesia |
Procedure: Erector Spinae Plane Block
Intravenous fentanyl patient control device 48-hour fentanyl consumption will be recorded.
|
| Active Comparator: Control group No regional anesthesia technique will be applied to the control group. |
Procedure: Intravenous fentanyl patient control device
Intravenous fentanyl patient control device 48-hour fentanyl consumption will be recorded.
|
Outcome Measures
Primary Outcome Measures
- Opioid consumption [Change from baseline opioid consumption at postoperative 0, 2, 4, 6, 12, 24, 36 and 48 hours]
The amount of fentanyl required by the patient and given by the device will be recorded for the first 48 hours.
Secondary Outcome Measures
- Visual Analog Scale [Change from baseline pain scores at postoperative 0, 2, 4, 6, 112, 24, 36 and 48 hours]
Pain of patients will be evaluated and recorded according to the Visual Analog Scale.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Donor patients scheduled for elective hepatectomy in liver transplantation surgery
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ASA I-II
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Patients who are aged between 18-65
Exclusion Criteria:
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Patients who do not accept the procedure
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Skin infection at the site of Erector Spina Plan Block area
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Coagulation disorder or using anticoagulant drugs
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Known local anesthetics and opioid allergy
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Severe pulmonary and/or cardiovascular problems
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Substance addiction or known psychiatric or mental problems
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Chronic painkiller usage
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Pregnancy or lactation
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Istanbul Medipol University Hospital | Istanbul | Turkey | 34070 |
Sponsors and Collaborators
- Medipol University
Investigators
- Principal Investigator: Tumay Uludag Yanaral, Medipol University
Study Documents (Full-Text)
None provided.More Information
Publications
- Chhibber A, Dziak J, Kolano J, Norton JR, Lustik S. Anesthesia care for adult live donor hepatectomy: our experiences with 100 cases. Liver Transpl. 2007 Apr;13(4):537-42.
- Dewe G, Steyaert A, De Kock M, Lois F, Reding R, Forget P. Pain management in living related adult donor hepatectomy: feasibility of an evidence-based protocol in 100 consecutive donors. BMC Res Notes. 2018 Nov 26;11(1):834. doi: 10.1186/s13104-018-3941-1.
- El-Boghdadly K, Pawa A. The erector spinae plane block: plane and simple. Anaesthesia. 2017 Apr;72(4):434-438. doi: 10.1111/anae.13830. Epub 2017 Feb 11.
- Hacibeyoglu G, Topal A, Arican S, Kilicaslan A, Tekin A, Uzun ST. USG guided bilateral erector spinae plane block is an effective and safe postoperative analgesia method for living donor liver transplantation. J Clin Anesth. 2018 Sep;49:36-37. doi: 10.1016/j.jclinane.2018.06.003. Epub 2018 Jun 5.
- Tsui BCH, Fonseca A, Munshey F, McFadyen G, Caruso TJ. The erector spinae plane (ESP) block: A pooled review of 242 cases. J Clin Anesth. 2019 Mar;53:29-34. doi: 10.1016/j.jclinane.2018.09.036. Epub 2018 Oct 3. Review.
- MEDIPOLU-973