A Study of Factors Influencing Recurrence After Thermal Ablation of Papillary Thyroid Carcinoma

Sponsor

Beijing Friendship Hospital (Other)

Overall Status

Recruiting

CT.gov ID

NCT05962892

Collaborator

(none)

600

Enrollment

Location

54.9

Anticipated Duration (Months)

10.9

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

A prospective cohort of papillary thyroid carcinoma(PTC), patients who received thermal ablation in our hospital since February 2023 was established as the study object. Preoperative and postoperative demographic data, ultrasonography, other relevant laboratory tests, and thyroid disease-related scales such as fatigue, depression, and stress were collected. The influencing factors of PTC recurrence were analyzed.

Condition or Disease	Intervention/Treatment	Phase
Papillary Thyroid Carcinoma Thermal Ablation	Other: No Intervention

Study Design

Study Type:

Observational [Patient Registry]

Anticipated Enrollment :

600 participants

Observational Model:

Cohort

Time Perspective:

Cross-Sectional

Official Title:

A Study of Factors Influencing Recurrence After Thermal Ablation of Papillary Thyroid Carcinoma

Anticipated Study Start Date :

Aug 1, 2023

Anticipated Primary Completion Date :

Feb 28, 2028

Anticipated Study Completion Date :

Feb 28, 2028

Arms and Interventions

Arm	Intervention/Treatment
No Intervention	Other: No Intervention No Intervention

Arm

Intervention/Treatment

No Intervention

Other: No Intervention

No Intervention

Outcome Measures

Primary Outcome Measures

the recurrence of PTC [1 to 5 years]
the recurrence of PTC during follow-up

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

①≥18 years old; ② Obtain informed consent; ③ Ultrasonography showed that malignant nodules were single, the maximum diameter of nodules was ≤1cm and the distance from the capsule was ≥2mm. ④ no lymph node metastasis or other extra-glandular metastasis in the neck; ⑤ PTC was confirmed by fine needle puncture pathology; ⑥ Patients who do not meet Article 3, who still strongly request thermal ablation while fully informing the patient of the risk of recurrence, and who have been clinically assessed to be technically capable of thermal ablation Exclusion Criteria:① Pregnant or lactating patients; ② Patients with other malignant tumors and not suitable for ablation by clinical evaluation; ③ Patients who cannot tolerate surgery; ④ Patients with cognitive impairment and other conditions who cannot accurately fill in thyroid-related questionnaires.