Clinical Profile of Parkinson's Disease in Patients With Hepatitis C Infection
Sponsor
Kasr El Aini Hospital (Other)
Overall Status
Unknown status
CT.gov ID
NCT03420573
Collaborator
(none)
300
24
Study Details
Study Description
Brief Summary
There is association between Hepatitis C and Parkinson's Disease as shown from previous studies. The clinical profile and natural history is not fully studied yet. We aim at studying the clinical characteristics of Parkinson's Disease in patients with hepatitis C infection.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
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Study Design
Study Type:
Observational [Patient Registry]
Anticipated Enrollment
:
300 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Clinical Profile of Parkinson's Disease in Patients With Hepatitis C Infection
Anticipated Study Start Date
:
Mar 1, 2018
Anticipated Primary Completion Date
:
Oct 1, 2019
Anticipated Study Completion Date
:
Mar 1, 2020
Outcome Measures
Primary Outcome Measures
- Score of UPDRS [2 years]
Severity of Motor and non motor symptoms
Eligibility Criteria
Criteria
Ages Eligible for Study:
50 Years
to 80 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- Patient with history of Parkinson's Disease and Hepatitis C infection.
Exclusion Criteria:
-
Advanced liver cirrhosis.
-
Patients with hepatic failure.
-
Symptoms of Parkinson's plus syndrome.
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Kasr El Aini Hospital
Investigators
- Study Director: Shaimaa I. El-Jaafary, MD, Director of Kasr Alainy Movement Disorders Unit KAMDU
Study Documents (Full-Text)
None provided.More Information
Publications
- Golabi P, Otgonsuren M, Sayiner M, Arsalla A, Gogoll T, Younossi ZM. The Prevalence of Parkinson Disease Among Patients With Hepatitis C Infection. Ann Hepatol. 2017 May - Jun;16(3):342-348. doi: 10.5604/16652681.1235476.
- Kim JM, Jang ES, Ok K, Oh ES, Kim KJ, Jeon B, Jo HJ, Ki M, Jeong SH. Association between hepatitis C virus infection and Parkinson's disease. Mov Disord. 2016 Oct;31(10):1584-1585. doi: 10.1002/mds.26755.
- Pakpoor J, Noyce A, Goldacre R, Selkihova M, Mullin S, Schrag A, Lees A, Goldacre M. Viral hepatitis and Parkinson disease: A national record-linkage study. Neurology. 2017 Apr 25;88(17):1630-1633. doi: 10.1212/WNL.0000000000003848. Epub 2017 Mar 29.
Responsible Party:
Shaimaa El-Jaafary,
Lecturer of Neurology,
Kasr El Aini Hospital
ClinicalTrials.gov Identifier:
NCT03420573
Other Study ID Numbers:
- KAMDUPDHC
First Posted:
Feb 5, 2018
Last Update Posted:
Feb 5, 2018
Last Verified:
Jan 1, 2018
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: