Cognitive Behavioral Therapy for Depression in Parkinson's Disease

• Sponsor: Oregon Health and Science University (Other)
• Overall Status: Terminated
• CT.gov ID: NCT00810628
• Collaborator: National Parkinson Foundation (Other)
• Enrollment: 12
• Location: 1
• Arm: 1
• Duration (Months): 11
• Patients Per Site Per Month: 1.1

Study Details

Study Description

Brief Summary

The purpose of this pilot program is to develop and evaluate a new treatment program for depression in Parkinson's disease (PD). The treatment uses Cognitive Behavior Therapy(CBT)to teach patients how to become more aware of their thoughts and feelings and to change thinking patterns and behaviors that may be related to depressive symptoms. This is the first time that this treatment has been used in a group setting for depression in PD.

Target population is patients in the Movement Disorders Clinic at Oregon Health & Science University who have Parkinson's disease and mild to moderate depression.

Condition or Disease	Intervention/Treatment	Phase
Parkinson's Disease; Depression	Behavioral: Cognitive Behavioral Therapy	N/A

Study Design

• Study Type: Interventional
• Actual Enrollment: 12 participants
• Allocation: N/A
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Primary Purpose: Supportive Care
• Official Title: Depression in Parkinson's Disease: A Pilot Project Using Cognitive Behavioral Therapy (CBT) to Improve Depression and Coping
• Study Start Date: Jan 1, 2009
• Actual Primary Completion Date: Sep 1, 2009
• Actual Study Completion Date: Dec 1, 2009

Arms and Interventions

Arm	Intervention/Treatment
Experimental: 1 All subjects in same investigative group with same CBT intervention.	Behavioral: Cognitive Behavioral Therapy; Individual interviews and group discussion/training.

Outcome Measures

Primary Outcome Measures

1. The change in CESD score [Baseline and 10 weeks]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 35 Years to 85 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Parkinson's disease, mild to moderate depression, seen at Oregon Health & Science University

Exclusion Criteria:

• Suicidal

• Cognitive impairment with MOCA <26

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Oregon Health & Science University	Portland	Oregon	United States	97239

Sponsors and Collaborators

• Oregon Health and Science University
• National Parkinson Foundation

Investigators

• Principal Investigator: Julie H. Carter, MS, Oregon Health and Science University
• Principal Investigator: Kristine Hanna, PhD, Oregon Health and Science University

Study Documents (Full-Text)

None provided.

More Information

Publications

• Dobkin RD, Allen LA, Menza M. Cognitive-behavioral therapy for depression in Parkinson's disease: a pilot study. Mov Disord. 2007 May 15;22(7):946-52.

• ClinicalTrials.gov Identifier: NCT00810628
• Other Study ID Numbers: OHSUIRB4613
• First Posted: Dec 18, 2008
• Last Update Posted: Oct 24, 2014
• Last Verified: Dec 1, 2008

• Keywords provided by , ,: Parkinson's disease; depression; Parkinson's disease with mild to moderate depression.
• Additional relevant MeSH terms: Parkinson Disease; Depression; Depressive Disorder

Study Results

No Results Posted as of Oct 24, 2014