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Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy

Sponsor
Bispebjerg Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT00404469
Collaborator
(none)
39
Enrollment
1
Location
3
Arms
20
Duration (Months)
1.9
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

We will investigate the effect of peritendinous corticosteroid injections, eccentric training and heavy resistance training in male patellar tendinopathy patients. The purpose is to compare the clinical effect of these three treatments in a randomised controlled trial. Also we wish to investigate the treatment mechanisms responsible for the effectiveness of the three treatments.

Condition or Disease Intervention/Treatment Phase
  • Procedure: peritendinous corticosteroid injections
  • Procedure: eccentric decline squat training
  • Procedure: heavy slow resistance training
 N/A

Detailed Description

3 interventions groups as described above (n=13 in each group) 12 weeks intervention period. Clinical assessments before and after intervention: VAS, VISA, Tendon thickness, Doppler us activity.

Before and after intervention tendon biopsies will be taken and analyzed for crosslinks and fibril diameter. Also tendon mechanical properties will be measured. Tendon and muscle structural properties will be measured with MRI.

Treatment satisfaction will be stated after intervention period.

Study Design

Study Type:
Interventional
Actual Enrollment :
39 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Single (Investigator)
Primary Purpose:
Basic Science
Official Title:
Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy
Study Start Date :
Mar 1, 2006
Actual Study Completion Date :
Nov 1, 2007

Arms and Interventions

Arm Intervention/Treatment
Active Comparator: CORT

Peritendinous corticosteroid injections at 0 and 4 weeks. 12 weeks total

Procedure: peritendinous corticosteroid injections
1 ml of40mg/ml methylprednisolone acetate at 0 and 4 weeks. 2 week observational
Experimental: ECC

12 weeks of eccentric unilateral decline squats

Procedure: eccentric decline squat training
eccentric decline unilateral squats performed twice daily. for 12 weeks
Experimental: HSR

Heavy slow resistance training. 3/week. 12 weeks

Procedure: heavy slow resistance training
Heavy slow resistance training for knee extensors. 3/week. total of 12 weeks

Outcome Measures

Primary Outcome Measures

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 55 Years
    Sexes Eligible for Study:
    Male
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • Clinical patellar tendinopathy pain.

    • Tendon swelling

    • Hypoechoic

    • Doppler activity in tendon

    Exclusion Criteria:

    • Previous knee surgery

    • diabetes

    • arthritis

    • previous steroid injections

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Institute of Sports Medicine Copenhagen. Dept 8 1st floor. Bispebjerg Hospital Copenhagen Denmark 2400

    Sponsors and Collaborators

    • Bispebjerg Hospital

    Investigators

    • Principal Investigator: Mads Kongsgaard, PhD., MSc., Institute of Sports Medicine, Copenhagen

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00404469
    Other Study ID Numbers:
    • Patellar tendinopathy
    First Posted:
    Nov 28, 2006
    Last Update Posted:
    May 22, 2008
    Last Verified:
    May 1, 2008
    Additional relevant MeSH terms:
    Tendinopathy

    Study Results

    No Results Posted as of May 22, 2008