Evaluations of Optimizing Perioperative Fluid Management on Postoperative Pain Outcomes

Sponsor

Kaohsiung Veterans General Hospital. (Other)

Overall Status

Completed

CT.gov ID

NCT02245581

Collaborator

(none)

Enrollment

Location

Arms

Study Details

Study Description

Brief Summary

Patient characteristics, duration of surgery, and infusion volumes will be compared between the groups. Oxygen transport and organ function will be compared Length of hospital stay, morbidity, postoperative pain intensity were compared. Continuous variables will be analyzed using the student t-test and discrete variables will be analyzed using Chi-Square test. P-value <0.05 will be considered significant, where appropriate 95% confidence intervals will be calculated. Statistical analysis will be carried out using standardize statistical programs SPSS 12.0 for windows.

Condition or Disease	Intervention/Treatment	Phase
Patients Major Laminectomy Surgery	Procedure: SVV-guided fluid management Procedure: CVP-guided fluid management	N/A

Study Design

Study Type:

Interventional

Actual Enrollment :

72 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Masking:

None (Open Label)

Primary Purpose:

Treatment

Study Start Date :

Apr 1, 2013

Actual Primary Completion Date :

Apr 1, 2014

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: SVV-guided fluid management SVV : Stoke volume variation	Procedure: SVV-guided fluid management
Active Comparator: CVP-guided fluid management CVP : Central venous pressure	Procedure: CVP-guided fluid management

Arm

Intervention/Treatment

Active Comparator: SVV-guided fluid management

SVV : Stoke volume variation

Procedure: SVV-guided fluid management

Active Comparator: CVP-guided fluid management

CVP : Central venous pressure

Procedure: CVP-guided fluid management

Outcome Measures

Primary Outcome Measures

Pain at rest and movement [Post-operation Day1 to Day4]

Eligibility Criteria

Criteria

Ages Eligible for Study:

20 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

All patients are undergoing elective spine laminectomy

Exclusion Criteria:

age <20 yr
emergency surgery
coagulopathy
renal and hepatic dysfunction
hyperthyroidism, and cardiac rhythm other than sinus rhythm

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Kaohsiung Veterans General Hospital	Kaohsiung		Taiwan	81362

Sponsors and Collaborators

Kaohsiung Veterans General Hospital.

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Yuan-Yi Chia, anesthesia doctor, Kaohsiung Veterans General Hospital.

ClinicalTrials.gov Identifier:

NCT02245581

Other Study ID Numbers:

VGHKS-102-036

First Posted:

Sep 19, 2014

Last Update Posted:

Sep 19, 2014

Last Verified:

Sep 1, 2014

Study Results

No Results Posted as of Sep 19, 2014