Patterns and Outcomes of Neurosurgery in England Over a Five-year Period

Sponsor
University of Leeds (Other)
Overall Status
Completed
CT.gov ID
NCT05097066
Collaborator
The Royal College of Surgeons of England (Other)
371,418
60

Study Details

Study Description

Brief Summary

Neurosurgical practice has seen many important changes over several decades with advances in treatments and the types of patients treated. Neurosurgical procedures have evolved, and as outcomes have improved the number of patients being treated has increased.

There are no recent evaluations of national neurosurgical practice in the United Kingdom (UK), with the last prospective cohort studies being Safe Neurosurgery 1993 and Safe Neurosurgery 2000. More recent studies of neurosurgical services have been based on data from single institutions or surgeons and these may not give a representative picture of practice nationally.

Recent national quality improvement programmes for neurosurgery in England (such as the National Neurosurgical Audit Programme (NNAP) and Cranial Neurosurgery and Spinal Surgery Getting It Right First Time (GIRFT) Programmes) have focused on using national hospital administrative datasets. To be effective, quality improvement initiatives require robust outcome measures and quality (process) indicators. Currently, there is a lack of validated quality indicators for neurosurgery, with practice often being described using generic measures such as readmission and reoperation rates and length of stay. Many studies have been able to derive these common outcome measures, but it may also be possible to produce indicators specific to neurosurgery.

The aim of this observational study was firstly to describe the current pattern of neurosurgical admissions and procedures in England, and thereby given an overview of the epidemiology of neurosurgical patients. Secondly, it aims to investigate the range of outcome measures that might be produced from hospital administrative data and use these to assess the quality of care in neurosurgery.

Study Design

Study Type:
Observational
Actual Enrollment :
371418 participants
Observational Model:
Cohort
Time Perspective:
Retrospective
Official Title:
Patterns and Outcomes of Neurosurgery in England Over a Five-year Period: a National Retrospective Cohort Study
Actual Study Start Date :
Apr 1, 2013
Actual Primary Completion Date :
Mar 31, 2018
Actual Study Completion Date :
Mar 31, 2018

Arms and Interventions

Arm Intervention/Treatment
Elective neurosurgery

Any elective neurosurgical procedure.

Procedure: Neurosurgical procedure
Any neurosurgical procedure in the National Neurosurgical Audit Programme (NNAP) Coding Framework of neurosurgical procedures.

Non-elective neurosurgery

Any non-elective neurosurgical procedure.

Procedure: Neurosurgical procedure
Any neurosurgical procedure in the National Neurosurgical Audit Programme (NNAP) Coding Framework of neurosurgical procedures.

Outcome Measures

Primary Outcome Measures

  1. Length of stay [From date of admission to date of discharge from hospital; assessed up to 60 months.]

    Length of the hospital admission to neurosurgery

  2. Additional inpatient neurosurgical procedure rate [From date of admission to date of discharge from hospital; assessed up to 60 months.]

    A further neurosurgical procedure in admissions where patients have had a primary (main) neurosurgical procedure.

  3. Proportion of patients discharged home [Determined on date of discharge from hospital; assessed up to 60 months.]

    Proportion of patients discharged to their normal address.

  4. In-patient mortality rate [From date of the neurosurgical procedure through date of death from any cause (in-patient deaths only); assessed up to 60 months.]

    In-patient mortality after a neurosurgical procedure.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • All admissions to neurosurgical units in the National Health Service (NHS) in England.
Exclusion Criteria:
  • Records with poor quality data (e.g. no data for clinical diagnoses).

  • Patients under 18 years that were admitted to an adult neurosurgical unit.

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • University of Leeds
  • The Royal College of Surgeons of England

Investigators

  • Study Chair: Ryan Mathew, University of Leeds

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Ryan Mathew, Associate Professor and Consultant Neurosurgeon, University of Leeds
ClinicalTrials.gov Identifier:
NCT05097066
Other Study ID Numbers:
  • NNAP002
First Posted:
Oct 27, 2021
Last Update Posted:
Oct 27, 2021
Last Verified:
Oct 1, 2021
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Oct 27, 2021