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TIMEX2: Effect of the Exercise-meal Timing on Energy Intake and Appetite in Adolescents With Obesity

Sponsor
University Hospital, Clermont-Ferrand (Other)
Overall Status
Completed
CT.gov ID
NCT03967782
Collaborator
AME2P Laboratory, Clermont Auvergne University (Other)
17
Enrollment
1
Location
1
Arm
2
Actual Duration (Months)
8.6
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The aim of the present study is to compare the effect of realizing an exercise right before or right after a meal of on energy intake, appetite feelings and food reward in adolescents with obesity.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: CON
  • Behavioral: EX-MEAL
  • Behavioral: MEAL-EX
 N/A

Detailed Description

The present study will compare the nutritional response to the realisation of an acute exercise right before or right after lunch in adolescents with obesity. 18 adolescents with obesity will be asked to randomly complete three experimental sessions: i) one control session (rest); ii) one session with an acute exercise realized right before lunch; iii) one session with an acute exercise realized right after lunch. Their ad libitum energy intake will be assessed during lunch as well as at dinner time. Appetite feelings will be assessed at regular intervals and their food reward in response to the lunch will also be assessed.

Study Design

Study Type:
Interventional
Actual Enrollment :
17 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
Effect of the Exercise-meal Timing on Energy Intake and Appetite in Adolescents With Obesity: the TIMEX 2 Study
Actual Study Start Date :
Aug 31, 2019
Actual Primary Completion Date :
Sep 29, 2019
Actual Study Completion Date :
Oct 30, 2019

Arms and Interventions

Arm Intervention/Treatment
Experimental: cohorte 1

18 adolescents with obesity are involved and will perform the three conditions.

Behavioral: CON
Control condition without exercise / rest condition. The adolescents will be asked to remain quiet and at rest during the morning and will receive an ad libitum meal at lunch and dinner times. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.
Other Names:
  • control condition without exercise / rest condition

    • Behavioral: EX-MEAL
    Condition with an acute exercise set right before lunch The adolescents will be asked to complete a 30 minutes exercise set at 65% of their capacities (cycling) right before ad ad libitum lunch meal. Lunch will be served ad libitum as well as diner. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.
    Other Names:
  • Condition with an acute exercise set right before lunch

    • Behavioral: MEAL-EX
    . condition with an acute exercise set right after lunch. The adolescents will be asked to complete a 30 minutes exercise set at 65% of their capacities (cycling) right after an ad libitul buffet meal. Lunch will be served ad libitum as well as diner. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.
    Other Names:
  • Condition with an acute exercise set right after lunch

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Change in energy intake measured during an ad libitum buffet meal (in kcal) [day 1 , day 8, day 15]

      food intake will be measured ad libitum during a lunch buffet. The adolescents will be offered an ad libitum buffet-type meal composed based on their food intake preferences. Their intake will be weighted using an electronic food scale by a member of the investigation team and then analysed using Bilnuts software.

    Secondary Outcome Measures

    1. Hunger feelings [day 1 , day 8, day 15]

      hunger area under the curve will be assessed using visual analogue scale through a the day

    2. Food reward [day 1 , day 8, day 15]

      The participants will be asked to complete a validated computer-based procedure to measure food reward (Leeds Food Preference Questionnaire; LFPQ) (Finlayson, King et al. 2008).

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    12 Years to 16 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • BMI percentile > 97th percentile according to the french curves.

    • ages 12-16 years old

    • Signed consent form

    • being registered in the national social security system

    • no contraindication to physical activity

    Exclusion Criteria:

    • Previous surgical interventions that is considered as non-compatible with the study.

    • Diabetes

    • weight loss during the last 6 months

    • cardiovascular disease or risks

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Chu Clermont Ferrand Clermont-Ferrand France 63003

    Sponsors and Collaborators

    • University Hospital, Clermont-Ferrand
    • AME2P Laboratory, Clermont Auvergne University

    Investigators

    • Principal Investigator: yves Boirie, University Hospital, Clermont-Ferrand

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    University Hospital, Clermont-Ferrand
    ClinicalTrials.gov Identifier:
    NCT03967782
    Other Study ID Numbers:
    • RBHP 2019 BOIRIE
    • 2019-A00507-50
    First Posted:
    May 30, 2019
    Last Update Posted:
    Jun 11, 2020
    Last Verified:
    Oct 1, 2019
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by University Hospital, Clermont-Ferrand
    appetite control
    obesity
    adolescents
    exercise timing
    Additional relevant MeSH terms:
    Obesity
    Pediatric Obesity

    Study Results

    No Results Posted as of Jun 11, 2020