ENDOMET: Percutaneous Imaging-guided Cryoblation of the Anterior Abdominal Wall Endometriosis Scars

Sponsor

University Hospital, Strasbourg, France (Other)

Overall Status

Recruiting

CT.gov ID

NCT06108167

Collaborator

(none)

Enrollment

Location

Anticipated Duration (Months)

4.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Endometriosis is a common condition affecting 10% of women. It is characterized by the presence of ectopic endometrial cells. This pathology most frequently develops in the ovaries, utero-sacral ligaments and pelvic peritoneum, but also in the recto-sigmoid. Rarely, these lesions are found outside the pelvis, and even more exceptionally in the abdominal wall (in 0.03 to 1% of cases).

Cryotherapy has already been used for many years to treat soft tissue tumors (kidney and prostate tumors). It has also been successfully used by interventional radiologists to treat parietal desmoid tumors. After discussions with radiologists, given the similarity of location and extension of wall endometriosis lesions with desmoid tumours, the successes observed, and the scarcity of studies in the literature, it seemed appropriate to the investigators to study this new therapy.

The aim of this study was to investigate the efficacy of cryotherapy on parietal endometriosis lesions.

Condition or Disease	Intervention/Treatment	Phase
Endometriosis

Study Design

Study Type:

Observational

Anticipated Enrollment :

29 participants

Observational Model:

Case-Only

Time Perspective:

Retrospective

Official Title:

Percutaneous Imaging-guided Cryoblation of the Anterior Abdominal Wall Endometriosis Scars

Actual Study Start Date :

May 5, 2023

Anticipated Primary Completion Date :

Nov 5, 2023

Anticipated Study Completion Date :

Nov 5, 2023

Outcome Measures

Primary Outcome Measures

Efficacy of cryotherapy on parietal endometriosis lesions was assessed using the a visual analogue scale (VAS) ranging from 0 to 10. [Before and 6 months after the cryotherapy]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

Female

Accepts Healthy Volunteers:

Inclusion Criteria:

Adult woman (≥18 years old) Having benefited from cryotherapy of an abdominal wall endometriosis nodule between January 6, 2020 and January 2, 2023.
Subject not objecting to the reuse of their data for the purposes of this research