Does Radial Artery Cannulation Affect the Perfusion Index(PI) of the Hand in Liver Transplant Operations?

• Sponsor: Inonu University (Other)
• Overall Status: Not yet recruiting
• CT.gov ID: NCT06077396
• Collaborator: (none)
• Enrollment: 50
• Arm: 1
• Anticipated Duration (Months): 3

Study Details

Study Description

Brief Summary

radial artery cannulation is performed by an experienced person, non-invasive blood pressure measurement will be made at 3 stages of the operation (dissection, anhepatic, neohepatic) and the effects of radial artery cannulation on the perfusion index will be evaluated by recording the correlation between radial artery and invasive measurements and the perfusion indexes of both hands simultaneously with Masimo.

Condition or Disease	Intervention/Treatment	Phase
Perfusion; Complications; Arterial Catheterization, Peripheral	Procedure: radial artery cannulation	N/A

Detailed Description

Arterial lines placement is for real-time monitoring of blood pressures and arterial blood sampling in critically ill patients or those undergoing complex procedures and surgeries.

Routine monitoring will be performed after the patients are taken to the operating room. Before bilateral radial artery cannulation, allen test will be performed and entrance perfusion indexes will be checked. After radial artery cannulation is performed by an experienced person, non-invasive blood pressure measurement will be made at 3 stages of the operation (dissection, anhepatic, neohepatic) and the effects of radial artery cannulation on the perfusion index will be evaluated by recording the correlation between radial artery and invasive measurements and the perfusion indexes of both hands simultaneously with Masimo.

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 50 participants
• Allocation: N/A
• Intervention Model: Single Group Assignment
• Intervention Model Description: Patients who underwent radial artery cannulation in liver transplantationPatients who underwent radial artery cannulation in liver transplantation
• Masking: None (Open Label)
• Primary Purpose: Prevention
• Official Title: Does Radial Artery Cannulation Affect the Perfusion Index of the Hand in Liver Transplant?
• Anticipated Study Start Date: Dec 1, 2023
• Anticipated Primary Completion Date: Jan 1, 2024
• Anticipated Study Completion Date: Mar 1, 2024

Arms and Interventions

Arm	Intervention/Treatment
Other: To evaluate the effect of radial artery cannulation on hand perfusion To evaluate the effect of radial artery cannulation on hand perfusion	Procedure: radial artery cannulation; radial artery cannulation

Outcome Measures

Primary Outcome Measures

1. To evaluate the perfusion index of the hand in which artery cannulation was performed with Masimo.There is no result range [Intraoperative (patients during surgery)]

   Arterial cannulation is mandatory for hemodynamic data monitoring in liver transplantation and is performed routinely. To evaluate the perfusion of the hand of the patients after cannulation

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 75 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

Patients undergoing liver transplantation Patients who will undergo intraarterial cannulation

Exclusion Criteria:

Peripheral vascular diseases Prior upper extremity surgery Radial artery injury

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• Inonu University

Investigators

• Principal Investigator: duygu demiröz, INONU UNİVERSİTY

Study Documents (Full-Text)

None provided.

More Information

Publications

• Brzezinski M, Luisetti T, London MJ. Radial artery cannulation: a comprehensive review of recent anatomic and physiologic investigations. Anesth Analg. 2009 Dec;109(6):1763-81. doi: 10.1213/ANE.0b013e3181bbd416.
• Numaguchi A, Adachi YU, Aoki Y, Ishii Y, Suzuki K, Obata Y, Sato S, Nishiwaki K, Matsuda N. Radial artery cannulation decreases the distal arterial blood flow measured by power Doppler ultrasound. J Clin Monit Comput. 2015 Oct;29(5):653-7. doi: 10.1007/s10877-014-9648-5. Epub 2014 Dec 16.

• Responsible Party: DUYGU DEMİROZ, Principal Investigator, Inonu University
• ClinicalTrials.gov Identifier: NCT06077396
• Other Study ID Numbers: LIVER TRANSP
• First Posted: Oct 11, 2023
• Last Update Posted: Oct 17, 2023
• Last Verified: Oct 1, 2023

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by DUYGU DEMİROZ, Principal Investigator, Inonu University: perfusion index; liver transplantation; radial artery cannulation

Study Results

No Results Posted as of Oct 17, 2023