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Locally Injected Vit D as a Non-surgical Modality for Periodontal Regeneration of Infrabony Defects

Sponsor
Cairo University (Other)
Overall Status
Completed
CT.gov ID
NCT03716765
Collaborator
(none)
20
Enrollment
2
Arms
29
Actual Duration (Months)

Study Details

Study Description

Brief Summary

vitamin D has great role in bone regenration and soft tissue health. in the past periodontal regeneration was performed using bone graft and barrier membrane

Condition or Disease Intervention/Treatment Phase
  • Dietary Supplement: locally injected vitamin D
 N/A

Detailed Description

there was no previous studies used the locally injected vitamin d in periodontal regeneration. therefore, we intended to study the effect of locally injected vitamin D in peridoontal regerneration in comparison with the conventional surgical technique

Study Design

Study Type:
Interventional
Actual Enrollment :
20 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Double (Care Provider, Investigator)
Primary Purpose:
Treatment
Official Title:
Locally Injected Vitamin D as a Non-surgical Modality for Periodontal Regeneration of Infrabony Defects: Prospective Study
Actual Study Start Date :
Jan 1, 2016
Actual Primary Completion Date :
Jan 1, 2018
Actual Study Completion Date :
Jun 1, 2018

Arms and Interventions

Arm Intervention/Treatment
Experimental: non-surgical periodontal regeneration

non-surgical periodontal regeneration using locally injected vitamin d to treat the infrabony defect

Dietary Supplement: locally injected vitamin D
locally injected vitamin d as non surgical method for periodontal regeneration of vertical bony defects
Other Names:
  • non-surgical periodontal rgeneration

    		•
    Active Comparator: surgical peridoontal regeneration

    surgical periodontal regeneration using bone graft and collagen barrier

    Dietary Supplement: locally injected vitamin D
    locally injected vitamin d as non surgical method for periodontal regeneration of vertical bony defects
    Other Names:
  • non-surgical periodontal rgeneration

    		•

    Outcome Measures

    Primary Outcome Measures

    1. radiographic interproximal bone level [6 months]

      radiographic interproximal bone level

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    20 Years to 45 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • patients with infrabony vertical defects

    • systemically free patients

    • periodontally affected patients

    Exclusion Criteria:

    • patients with systemic diseases

    • smokers

    • pregnency

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • Cairo University

    Investigators

    • Study Director: nermin yussif, october university of modern sciences and arts

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    nermin mohammed ahmed yussif, assistant lecturer, Cairo University
    ClinicalTrials.gov Identifier:
    NCT03716765
    Other Study ID Numbers:
    • 1236
    First Posted:
    Oct 23, 2018
    Last Update Posted:
    Oct 23, 2018
    Last Verified:
    Oct 1, 2018
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Product Manufactured in and Exported from the U.S.:
    No
    Additional relevant MeSH terms:
    Alveolar Bone Loss
    Periodontal Pocket
    Vitamin D

    Study Results

    No Results Posted as of Oct 23, 2018