Photodynamic Lasertherapy (PDT) in Periodontal Treatment (in Vivo)

• Sponsor: University Medicine Greifswald (Other)
• Overall Status: Completed
• CT.gov ID: NCT00196456
• Collaborator: (none)
• Enrollment: 60
• Location: 1
• Duration (Months): 9
• Patients Per Site Per Month: 6.6

Study Details

Study Description

Brief Summary

The purpose of the study is to evaluate the effect of the photodynamic therapy in periodontal patients

Condition or Disease	Intervention/Treatment	Phase
Periodontal Disease	Procedure: photosensitisation	Phase 2

Detailed Description

The purpose of the study is to evaluate the effect of the photodynamic therapy in periodontal pockets and to assess the reduction of subgingival bacteria.

The first step will include the evaluation of the quantity of the light which will activate the photosensitizer in the various niches in the periodontal pocket.

The second step will evaluate the distribution of the photosensitizer in the periodontal pocket.

The third step will assess the woundhealing of the the photodynamic therapy compared to conventional periodontal therapy with an ultrasonic device.

Study Design

• Study Type: Interventional
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Double
• Primary Purpose: Treatment
• Official Title: Photodynamic Lasertherapy (PDT) in Periodontal Treatment (in Vivo)
• Study Start Date: Apr 1, 2004
• Study Completion Date: Jan 1, 2005

Outcome Measures

Primary Outcome Measures

1. pocket depth reduction []

Secondary Outcome Measures

1. attachmentlevel loss []

Eligibility Criteria

Criteria

• Ages Eligible for Study: 35 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• systemic healthy

• 15 teeth

• ≤ 6 mm >2 teeth

• age > 35 years

Exclusion Criteria:

• • systemic ill

• cardiac pacemaker

• < 15 teeth

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Ernst-Moritz-Arndt-Universität Greifswald	Greifswald	Mecklenburg-Vorpommern	Germany	17489

Sponsors and Collaborators

• University Medicine Greifswald

Investigators

• Principal Investigator: Thomas Kocher, Prof.Dr., Ernst-Moritz-Arndt University Greifswald

Study Documents (Full-Text)

None provided.

More Information

Publications

• Kömerik N, Wilson M, Poole S. The effect of photodynamic action on two virulence factors of gram-negative bacteria. Photochem Photobiol. 2000 Nov;72(5):676-80.

• ClinicalTrials.gov Identifier: NCT00196456
• Other Study ID Numbers: III UV 06/04
• First Posted: Sep 20, 2005
• Last Update Posted: Sep 20, 2005
• Last Verified: Sep 1, 2005

• Keywords provided by , ,: Photodynamic lasertherapy; Periodontol disease
• Additional relevant MeSH terms: Periodontal Diseases

Study Results

No Results Posted as of Sep 20, 2005