Insulin Versus Hyaluronic Acid in Management of Periodontal Defects
Sponsor
October University for Modern Sciences and Arts (Other)
Overall Status
Recruiting
CT.gov ID
NCT05746676
Collaborator
(none)
30
1
2
8.6
3.5
Study Details
Study Description
Brief Summary
in this study, insulin and hyaluronic acid will be used after open flap debridement in treatment of periodontal defects. outcome will be evaluated clinically and radiographically
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Phase 3 |
Detailed Description
n this study, insulin versus hyaluronic acid will be used after open flap debridement in treatment of periodontal defects. outcome will be evaluated clinically and radiographically after a follow up period
Study Design
Study Type:
Interventional
Anticipated Enrollment
:
30 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Triple (Care Provider, Investigator, Outcomes Assessor)
Primary Purpose:
Treatment
Official Title:
Clinical and Radiographic Evaluation of Insulin Versus Hyaluronic Acid in Management of Periodontal Defects
Actual Study Start Date
:
Jan 12, 2023
Anticipated Primary Completion Date
:
Aug 1, 2023
Anticipated Study Completion Date
:
Oct 1, 2023
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: group 1
|
Drug: Insulin
in treatment of periodontal defects
|
| Active Comparator: group 2
|
Drug: Hyaluronic acid
in treatment of periodontal defects
|
Outcome Measures
Primary Outcome Measures
- clinical evaluation [6 months]
periodontal pocket depth
- radiographic evaluation [6 months]
bone gain assessed by cone beam computed tomography
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
to 65 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
- patients diagnosed with periodontitis
Exclusion Criteria:
- patients with systemic illness that contraindicate periodontal surgery
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Al-Azhar University, Faculty of Dentistry | Cairo | Egypt |
Sponsors and Collaborators
- October University for Modern Sciences and Arts
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Naglaa Elwakeel,
professor,
October University for Modern Sciences and Arts
ClinicalTrials.gov Identifier:
NCT05746676
Other Study ID Numbers:
- P-ME-23-01
First Posted:
Feb 28, 2023
Last Update Posted:
Feb 28, 2023
Last Verified:
Feb 1, 2023
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Product Manufactured in and Exported from the U.S.:
No
Keywords provided by Naglaa Elwakeel,
professor,
October University for Modern Sciences and Arts
Additional relevant MeSH terms: