BMP-2 and ALP Levels Following Laser Therapy With Scaling and Root Planing in Periodontitis- RCT.
Sponsor
Cairo University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05555420
Collaborator
(none)
20
2
13
Study Details
Study Description
Brief Summary
Patients with periodontitis will be treated by either SRP only or SRP in combination with laser.
Samples from GCF will be collected immediately after treatment and at 3 months follow-up time. Levels of BMP-2 and ALP will be assessed at these time points.
Statistical analysis to compare the results will be performed.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Study Type:
Interventional
Anticipated Enrollment
:
20 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Single (Outcomes Assessor)
Primary Purpose:
Treatment
Official Title:
Assessment of BMP-2 and ALP Levels Following Laser Therapy as an Adjunct to Scaling and Root Planing for Treatment of Periodontitis- A Randomized Clinical Trial.
Anticipated Study Start Date
:
Nov 1, 2022
Anticipated Primary Completion Date
:
Jul 1, 2023
Anticipated Study Completion Date
:
Dec 1, 2023
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: SRP only
|
Device: SRP+Laser
Non-surgical periodontal therapy in combination with Laser
|
| Experimental: SRP+Laser
|
Device: SRP+Laser
Non-surgical periodontal therapy in combination with Laser
|
Outcome Measures
Primary Outcome Measures
- Amount of attachment gain [3 months]
Described in mm
Secondary Outcome Measures
- Level of BMP-2 in GCF [3 months]
ELISA test
- Level of ALP in GCF [3 months]
Colorimetry
Eligibility Criteria
Criteria
Ages Eligible for Study:
N/A
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- Periodontitis
Exclusion Criteria:
- Uncontrolled medical condition
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Cairo University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Marwa El Sayed Abbas Ahmed,
Dr.,
Ahram Canadian University
ClinicalTrials.gov Identifier:
NCT05555420
Other Study ID Numbers:
- ACU-Dentistry-Perio.1
First Posted:
Sep 26, 2022
Last Update Posted:
Sep 26, 2022
Last Verified:
Sep 1, 2022
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
Yes
Additional relevant MeSH terms: