APEX: Petro-trigeminal Line and Petrous Apex Cephaloceles

Sponsor

University Hospital, Strasbourg, France (Other)

Overall Status

Recruiting

CT.gov ID

NCT05639491

Collaborator

(none)

209

Enrollment

Location

27.4

Anticipated Duration (Months)

7.6

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

cephaloceles are rare lesions of the petrous apex, inconsistently listed as meningoceles or arachnoid cysts. They're consistent with a herniation posterolateral of the Meckel cavum within the petrous apex. These lesions may be the cause of a symptomatology varied, or be discovered by chance in subjects who have not been asymptomatic. Currently, there is no evidence in the literature a simple, fast and reproducible radiological marker that allows for the diagnosis of cephaloceles of the petrous apex, in particular the small ones. The purpose of this study is to validate a radiological benchmark simple and reproducible, the trigeminal petrol line, in order to improve the diagnosis of petrous apex cephaloceles

Condition or Disease	Intervention/Treatment	Phase
Petrous Apex Meningioma

Study Design

Study Type:

Observational

Anticipated Enrollment :

209 participants

Observational Model:

Case-Only

Time Perspective:

Retrospective

Official Title:

The Petro-trigeminal Line: a Simple Radiological Marker for the Diagnosis of Cephaloceles of the Petrous Apex on MRI

Actual Study Start Date :

Sep 18, 2020

Anticipated Primary Completion Date :

Dec 1, 2022

Anticipated Study Completion Date :

Dec 31, 2022

Outcome Measures

Primary Outcome Measures

Validate a radiological landmark allowing MRI diagnosis cephaloceles of the petrous apex [Files analysed retrospectively from from January 01, 2003 to September 31, 2020 will be examined]
This mark corresponds to the projection of a line drawn on an axial section, in the plane of the posterior roots of the trigeminal nerves, between the anterior and external edges of the petrous apex along the petro-trigeminal angle on each side.

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Inclusion criteria:

Major subjects (≥18 years old)
patients who underwent an MRI with high resolution 3D T2 sequence between 01/01/2003 and 09/31/2020:
200 patients consulting for ENT pathology such as vertigo
9 patients presenting the radiological criteria in MRI of a cephalocele of the petrous apex according to the current data of the literature on a T2 3D HR sequence
- Subject who has not expressed his opposition, after being informed, to the reuse of his data for the purposes of this research.