Platform for Medical Information Extraction From Incomplete Data

Sponsor
National Taiwan University Hospital (Other)
Overall Status
Unknown status
CT.gov ID
NCT01813942
Collaborator
National Science Council, Taiwan (Other)
10,000
1
36
277.7

Study Details

Study Description

Brief Summary

In order to perform research smoothly, the process of information extraction is required for translating data in clinical text into available format for analysis and statistic. In medical research, the problem of missing data occurs frequently. It is important to develop the method with better imputation performance in the stability and accuracy. The purposes of this project are to provide the data integration and extraction methods for handling the structured and unstructured data sources in more efficient ways, to provide the validation scheme for facilitating the data reviewing of extracted results produced by information extraction modules, to increase the quality of clinical data by comparing the data from different data sources and correcting data errors and inconsistent, to handle the clinical data with the properties of time series and incompleteness, to increase accuracy of data analysis and increase quality of health care by improving the completeness and correctness of clinical data, to provide flexibility of methods in the platform. In the project, the disease topic is focused on the liver cancer patients' clinical data and we hope the methods in the projects can be extended to handle other diseases by replacing these knowledge models in the future.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Because of the increasing adoption of Electronic Medical Record (EMR) systems, the data access of EMR is more and more convenient. However, there still have difficulties in analyzing all the clinical data directly due to a large number of records using the narrative format. In order to perform research smoothly, the process of information extraction is required for translating data in clinical text into available format for analysis and statistic. In medical research, the problem of missing data occurs frequently. It is important to develop the method with better imputation performance in the stability and accuracy. The purposes of this project are to provide the data integration and extraction methods for handling the structured and unstructured data sources in more efficient ways, to provide the validation scheme for facilitating the data reviewing of extracted results produced by information extraction modules, to increase the quality of clinical data by comparing the data from different data sources and correcting data errors and inconsistent, to handle the clinical data with the properties of time series and incompleteness, to increase accuracy of data analysis and increase quality of health care by improving the completeness and correctness of clinical data, to provide flexibility of methods in the platform. In the project, the disease topic is focused on the liver cancer patients' clinical data and we hope the methods in the projects can be extended to handle other diseases by replacing these knowledge models in the future.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    10000 participants
    Time Perspective:
    Retrospective
    Official Title:
    Platform for Medical Information Extraction From Incomplete Data
    Study Start Date :
    Mar 1, 2013
    Anticipated Primary Completion Date :
    Mar 1, 2016
    Anticipated Study Completion Date :
    Mar 1, 2016

    Outcome Measures

    Primary Outcome Measures

    1. The number of patients correctly identified by recurrence predictive model [3 years]

      The recurrence predictive model is developed using the incomplete data set, this model is used for predicting the recurrent status of patient who received the specific treatment for liver cancer. The number of patients correctly identified by recurrence predictive model is regarded as the primary outcome measure.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    N/A and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No

    Patients with liver cancer

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 National Taiwan University Hospital Taipei Taiwan

    Sponsors and Collaborators

    • National Taiwan University Hospital
    • National Science Council, Taiwan

    Investigators

    • Principal Investigator: Feipei Lai, National Taiwan University

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    National Taiwan University Hospital
    ClinicalTrials.gov Identifier:
    NCT01813942
    Other Study ID Numbers:
    • 201302013RINC
    First Posted:
    Mar 19, 2013
    Last Update Posted:
    Oct 28, 2013
    Last Verified:
    Oct 1, 2013
    Keywords provided by National Taiwan University Hospital
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Oct 28, 2013