Portsmouth CORE-D Routine Care Data Repository
Study Details
Study Description
Brief Summary
An integrated database of depersonalised routine hospital patient data consisting of demographic and disease attributes, physiological or laboratory measurements, care contacts and interventions along with associated clinical outcomes. The database is an essential resource for the development and testing of risk models and classification systems, modified as necessary for patient subgroups, which can then be introduced into clinical care to improve patient outcomes. It can also be used for large scale simulations to evaluate interventions.
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Detailed Description
The aims and objectives of this database of depersonalised routinely collected hospital patient data are to:
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Conduct epidemiological and observational studies of acute hospital care.
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Develop and use algorithms and risk models to identify the deteriorating / sick adult so that interventions and enhanced care can be provided in a timelier manner with consequent resource and outcome improvements. This covers both the deteriorating inpatient at risk of adverse outcomes and people in the local community at risk of hospitalisation or in need of other health services.
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Retrospectively evaluate interventions e.g. impact of system-wide clinical pathway introduction
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Conduct simulations of clinical pathways
Study Design
Outcome Measures
Primary Outcome Measures
- In-hospital death [At 24 hours after an observation assessment or physiological measurement]
Death during hospital admission
- In-hospital death [30 days after admission]
Death during hospital admission
- Unanticipated ICU admission [At 24 hours after an observation assessment or physiological measurement]
Unanticipated ICU admission during hospital stay
- Unanticipated ICU admission [30 days after admission]
Unanticipated ICU admission during hospital stay
- Cardiac arrest [At 24 hours after an observation assessment or physiological measurement]
Cardiac arrest during hospital stay
- Cardiac arrest [30 days after admission]
Cardiac arrest during hospital stay
Secondary Outcome Measures
- Diagnosis of Corona Virus Disease (COVID) infection [48 hours after presentation]
Diagnosis of COVID-19
- Diagnosis of Corona Virus Disease (COVID) infection [At 48 hours after an observation assessment or physiological measurement]
Diagnosis of COVID-19
- Detection of Acute Organ Dysfunction [24 hours after presentation]
Detection of acute organ dysfunction as measured by components of the Sequential Organ Failure Assessment (SOFA) Score
- Detection of Acute Organ Dysfunction [48 hours after presentation]
Detection of acute organ dysfunction as measured by components of the Sequential Organ Failure Assessment (SOFA) Score
- Detection of Acute Organ Dysfunction [72 hours after presentation]
Detection of acute organ dysfunction as measured by components of the Sequential Organ Failure Assessment (SOFA) Score
- Detection of Acute Organ Dysfunction [1 week after presentation]
Detection of acute organ dysfunction as measured by components of the Sequential Organ Failure Assessment (SOFA) Score
- Detection of Acute Organ Dysfunction [30 days after presentation]
Detection of acute organ dysfunction as measured by components of the Sequential Organ Failure Assessment (SOFA) Score
Eligibility Criteria
Criteria
Inclusion Criteria:
- Adult presenting at the acute hospital or receiving services from the hospital
Exclusion Criteria:
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Adults who have registered an opt out of research with National Health Service (NHS) Digital
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Adults who have contacted the hospital to ask that their records are not to be included in this study
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Portsmouth Hospitals NHS Trust
Investigators
- Principal Investigator: Paul E Schmidt, MRCP, Portsmouth Hospitals University NHS Trust
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- PHU/2021/11