Use Bronchoscopy to Predict Post-Extubation Stridor in Critical Ill Patients

• Sponsor: Chimei Medical Center (Other)
• Overall Status: Unknown status
• CT.gov ID: NCT00824096
• Collaborator: (none)
• Enrollment: 100
• Location: 1
• Duration (Months): 36
• Patients Per Site Per Month: 2.8

Study Details

Study Description

Brief Summary

Our study aims at the accuracy of bronchoscopy to predict PES. Evidence base medicine guidelines for extubation may be obtained through this study.

Condition or Disease	Intervention/Treatment	Phase
Post-Extubation Stridor	Procedure: Bronchoscopy	N/A

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 100 participants
• Allocation: Non-Randomized
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Primary Purpose: Prevention
• Study Start Date: Dec 1, 2006
• Anticipated Primary Completion Date: Dec 1, 2009
• Anticipated Study Completion Date: Dec 1, 2009

Outcome Measures

Primary Outcome Measures

1. The accuracy of bronchoscopy to predict post-extubation stridor. [48 hours]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Age equal or greater than 18 years old

• Intubation over 24 hrs

• Match weaning profile

• Cuff leak volume less than 24%

• VS and subject/family agree

Exclusion Criteria:

• Re-Intubation

• History of upper air way obstruction

• Severe CV disease (ex. AMI)

• Active UGI Bleeding

• Blood sugar persistent more than 250 mg/dl under medication control

• Risk of IICP

• Open T.B.

• Bleeding tendency/ Platelet less than 40 thousands

• Subject or family refuse

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Department of Intensive Care Medicine; Chi Mei Medical Center	Tainan		Taiwan	710

Sponsors and Collaborators

• Chimei Medical Center

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• ClinicalTrials.gov Identifier: NCT00824096
• Other Study ID Numbers: CM-IRB09512014
• First Posted: Jan 16, 2009
• Last Update Posted: Jan 16, 2009
• Last Verified: Jan 1, 2009

• Keywords provided by , ,: endotracheal intubation; cuff-leak test; post-extubation stridor; bronchoscopy; corticosteroids; Cuff-leak volume less than 24%
• Additional relevant MeSH terms: Respiratory Sounds

Study Results

No Results Posted as of Jan 16, 2009