EOINBvsESB: Ultrasound Guided Erector Spinae Plane Block vs External Oblique Intercostal Plane Block for Nephrectomy
Study Details
Study Description
Brief Summary
The patients will be randomly allocated into two equal groups using a computer program.
Group A: will receive U S guided external oblique intercostal block after induction.
Group B:
Patients will receive US guided erector spine block after induction.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
Patients will be premedicated with IV midazolam (0.05 mg/kg). Under standard monitoring including Electrocardiography, Non-Invasive Blood Pressure, and Pulse Oximetry. General Anesthesia will be induced with Fentanyl (1-2 μg/kg), Propofol (2-3 mg/kg), and Atracurium (0.5-0.8 mg/kg). Pressure controlled Volume guarantee Ventilation mode will be used to maintain O2 Saturation Above 98%. Anesthesia will be maintained with Isoflurane 1.2 Minimum Alveolar Concentration inhalation
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: external oblique intercostal block After induction of general anesthesia, external oblique intercostal blocks will be performed with patients positioned in the supine position with their ipsilateral arm abducted. A 14-15 MHz linear ultrasound transducer (Sono-Site) was placed in the sagittal plane between the midclavicular and anterior axillary lines at the level of sixth rib. 30 ml of bupivacaine 0.25% will be administered incrementally. The drug will be injected after a negative aspiration into the plane deep to the external oblique muscle and superficial to the sixth and seventh ribs and their associated intercostal muscles. |
Procedure: external oblique intercostal block
U S guided external oblique intercostal block after induction.
|
| Active Comparator: Erector Spine Block After induction of general anesthesia, patients will be positioned in the lateral position . A linear ultrasound transducer will be placed on the midline to identify the T8 spinous process. From this position, the ultrasound transducer was moved 2-3 cm laterally to visualize the hyperechoic line of the T8 transverse process with its associated acoustic shadow inferiorly, and the overlying erector spinae muscle superiorly. 30 ml 0.25% bupivacaine will be injected. |
Procedure: Erector Spine block
US guided erector spine block after induction
|
Outcome Measures
Primary Outcome Measures
- time for first rescue analgesia [day 0]
hours
Secondary Outcome Measures
- visual analogue score VAS score [24 hours]
(a scale from 0 to 10 where 0 is interpreted as no pain, 1-4 mild pain, 5-6 moderate pain, 7-10 severe pain) will be recorded 15 min after extubation (as soon as the patient will be alert enough to report pain)
- the number of rescue analgesics [24hours]
numbers'
Eligibility Criteria
Criteria
Inclusion Criteria:
- Eligible patients will be older than 21 years old with American society of anesthesiology ASA physical status I& II&III scheduled for elective (Subcostal) Nephrectomy
Exclusion Criteria:
-
Patients who are:
-
Uncooperative.
-
Having allergy to any of the study drugs.
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Known abuse of alcohol or medication.
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Having Local infection at the site of injection or systemic infection.
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Pregnancy.
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With coagulation disorders or on anticoagulation therapy.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Menoufia university | Cairo | Shibin Elkom | Egypt |
Sponsors and Collaborators
- Menoufia University
Investigators
- Principal Investigator: AMAL G SAFAN, MD, Menoufia University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 9/2023ANET1-2