EFFECT OF ANESTHESİA TECHNIQUES ON POSTOPERATİVE COGNİTİVE DYSFUNCTION FOR MMSE AND NSE LEVEL

• Sponsor: Erzincan University (Other)
• Overall Status: Unknown status
• CT.gov ID: NCT04279132
• Collaborator: (none)
• Enrollment: 80
• Location: 1
• Anticipated Duration (Months): 4
• Patients Per Site Per Month: 20

Study Details

Study Description

Brief Summary

The aim of this study is to compare the effects of total intravenous anesthesia and inhalation anesthesia methods on postoperative cognitive dysfunction according to Mini Mental State Examination scores and Neuron Specific Enolase levels in lumbar disc herniectomy operations.

Condition or Disease	Intervention/Treatment	Phase
Postoperative Cognitive Dysfunction; NEURON SPECIFIC ENOLASE; MINI MENTAL STATE EXAMINATION TEST	Behavioral: POSTOPERATIVE COGNITIVE DYSFUNCTION

Study Design

• Study Type: Observational [Patient Registry]
• Anticipated Enrollment: 80 participants
• Observational Model: Cohort
• Time Perspective: Prospective
• Official Title: THE EFFECT OF TOTAL INTRAVENOUS ANESTHESIA AND INHALATION ANESTHESIA TECHNIQUES FOR MINI MENTAL STATE EXAMINATION TEST AND NEURON SPECIFIC ENOLASE LEVEL IN LUMBAR DISK HERNIECTOMY OPERATIONS
• Anticipated Study Start Date: Mar 21, 2020
• Anticipated Primary Completion Date: May 21, 2020
• Anticipated Study Completion Date: Jul 21, 2020

Arms and Interventions

Arm	Intervention/Treatment
TOTAL INTRAVENOUS ANESTHESIA	Behavioral: POSTOPERATIVE COGNITIVE DYSFUNCTION; NEURON SPECIFIC ENOLASE LEVELS IN LUMBAR DISC HERNIECTOMY WITH GENERAL ANESTHESIA MODALITIES
INHALATION ANESTHESIA	Behavioral: POSTOPERATIVE COGNITIVE DYSFUNCTION; NEURON SPECIFIC ENOLASE LEVELS IN LUMBAR DISC HERNIECTOMY WITH GENERAL ANESTHESIA MODALITIES

Outcome Measures

Primary Outcome Measures

1. MINI MENTAL STATE EXAMINATION TEST [1 MONTH]

   BELOW 27 SCORE IS ASSOSIATED WITH POSTOPERATIVE COGNITIVE DYSFUNCTION

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 65 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

-Lumbal disc herniectomy operation 18-65 age

Exclusion Criteria:

• Patients before and after the coronary artery bypass graft surgery

• patients in the last trimester of pregnancy

• patients with severe heart failure

• liver failure

• kidney failure

• malignant hyperthermia

• lactating patients

• patients with vision or hearing problems

• patients having difficulty in understanding and speaking Turkish

• Parkinson's and Alzheimer's disease

• alcohol and drug addicts

• morbidly obese patients

• intraoperative hypotension, hypertension and hypoxemia

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Erzincan Byu	Erzincan		Turkey

Sponsors and Collaborators

• Erzincan University

Investigators

• Principal Investigator: TÜLAY CEREN ÖLMEZTÜRK KARAKURT, ERZINCAN BYU

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: TULAY CEREN OLMEZTURK KARAKURT, MD, Erzincan University
• ClinicalTrials.gov Identifier: NCT04279132
• Other Study ID Numbers: 19/10
• First Posted: Feb 20, 2020
• Last Update Posted: Feb 20, 2020
• Last Verified: Feb 1, 2020

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Postoperative Cognitive Complications; Cognitive Dysfunction

Study Results

No Results Posted as of Feb 20, 2020