Ropivacaine Use in Interscalene Block; What is the Minimal Effective Analgesic Concentration (MEAC 90)
Study Details
Study Description
Brief Summary
This study aim to calculate the minimal effective ropivacaine concentration required achieve successful analgesic interscalene block in 90% of patients (MEAC90)
Condition or Disease | Intervention/Treatment | Phase |
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Phase 4 |
Detailed Description
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Before induction of general anesthesia, all patients will receive interscalene block using 15ml of ropivacaine which concentration will be based on the response of the previous patient.
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Based on biased-coin design up-down sequential method: if patient has pain free recovery, a successful block, the next patient will be randomized to receive either the same ropivacaine concentration or a concentration 0.01% w/v less. However, if he has an unsuccessful block, the next patient will receive a concentration 0.01% w/v higher.
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Patients with pain free recovery will be considered to have positive response.
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Patients' responses will be analyzed to calculate the MEAC90.
Study Design
Outcome Measures
Primary Outcome Measures
- effective analgesic interscalene block [in recovery unit (one hour after surgery)]
postoperative pain (will be assessed using numerical rating scale. if ≥ 3, ineffective block will be considered and if <3, an effective block will be considered
Eligibility Criteria
Criteria
Inclusion Criteria:
- Patients, who are scheduled for shoulder arthroscopy
Exclusion Criteria:
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- <18 y,
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ASA physical class greater >III
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BMI >40 has any contraindication for medications or techniques used in the study
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Healthpoint Hospital | Abu Dhabi | United Arab Emirates | 112308 |
Sponsors and Collaborators
- Healthpoint Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- MF2467-2021-15