Effect of Intrathecal vs Intraarticular Dexmedetomidine on Postoperative Pain Following Arthroscopy

• Sponsor: Assiut University (Other)
• Overall Status: Completed
• CT.gov ID: NCT02581566
• Collaborator: (none)
• Enrollment: 90
• Location: 1
• Arms: 3
• Duration (Months): 9
• Patients Per Site Per Month: 10

Study Details

Study Description

Brief Summary

Comparison between intrathecal Dexmedetomidine versus Intraarticular Dexmedetomidine on postoperative pain after knee arthroscopy.

Condition or Disease	Intervention/Treatment	Phase
Postoperative Pain	Drug: Intrathecal Dexmedetomidine; Drug: Intraarticular Dexmedetomidine; Drug: Bupivacaine	N/A

Study Design

• Study Type: Interventional
• Actual Enrollment: 90 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
• Primary Purpose: Prevention
• Study Start Date: Jul 1, 2015
• Actual Primary Completion Date: Apr 1, 2016
• Actual Study Completion Date: Apr 1, 2016

Arms and Interventions

Arm	Intervention/Treatment
Active Comparator: Intrathecal Dexmedetomidine Group 30 patients will be given Intrathecal Dexmedetomidine plus Intrathecal Bupivacaine	Drug: Intrathecal Dexmedetomidine; Addition of Intathecal Dexmedetomidine plus Intrathecal Bupivacaine
Active Comparator: Intraarticular Dexmedetomidine Group 30 patients will be given Intraarticular Dexmedetomidine plus Intrathecal Bupivacaine	Drug: Intraarticular Dexmedetomidine; Addition of Intraarticular Dexmedetomidine plus Intrathecal Bupivacaine
Other: control Group 30 patients will be given Intrathecal Bupivacaine	Drug: Bupivacaine; Intrathecal Bupivacaine

Outcome Measures

Primary Outcome Measures

1. postoperative pain [24 hours]

   Assesment is done by Visual Analog Scale

Secondary Outcome Measures

1. c-reactive protein [24 hours]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 20 Years to 50 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Adult patients, ASA I-II, undergoing knee arthroscopy under spinal anesthesia.

Exclusion Criteria:

• Absolute or relative contraindications to spinal anesthesia, allergy to dexmedetomidine or chronic pain treatment.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Assiut University Hospital	Assiut		Egypt	71515

Sponsors and Collaborators

• Assiut University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Eman A. Ismail, Lecturer, Assiut University
• ClinicalTrials.gov Identifier: NCT02581566
• Other Study ID Numbers: 01003060215
• First Posted: Oct 21, 2015
• Last Update Posted: Mar 13, 2019
• Last Verified: Mar 1, 2019

• Additional relevant MeSH terms: Pain, Postoperative; Dexmedetomidine; Bupivacaine

Study Results

No Results Posted as of Mar 13, 2019