Effect of Saline Lubrication on Post-intubation Complications
Study Details
Study Description
Brief Summary
The purpose of this study is to evaluate the influence of none-lubricated dry tube on the incidence of Postoperative Sore Throat (POST) after general anesthesia with endotracheal intubation.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Saline group In the saline group, disposable endotracheal tube was immersed in the 1 liter of sterile 0.9% sodium chloride irrigation solution before anesthetic induction. |
Procedure: Saline group
After anesthetic induction, patients will be intubated with endotracheal tube which was immersed in normal saline before intubation.
|
| Experimental: Dry group In the dry group, endotracheal tube was peeled off from sterile packing just before orotracheal intubation. |
Procedure: Dry group
After anesthetic induction, patients will be intubated with endotracheal tube which was not immersed in normal saline.
|
Outcome Measures
Primary Outcome Measures
- incidence of postoperative sore throat (POST) [until one day after surgery]
ask patients whether they have sore throat after surgery
Secondary Outcome Measures
- Oropharyngeal injury [2 hours and 24 hours after surgery]
assessed by direct visualization of the oropharyngeal cavity with regard to the location such as pharyngeal wall, uvula, vallecular, tonsillar fossa and pillars and presence of hyperemia, edema, hematoma, or any other lesions
- respiratory symptoms [1 week after the surgery]
At the 1 week postoperative follow-up phone call, patients would be asked if they have upper respiratory symptoms such as cough, sputum, sore throat or fever. And if so, they would be checked if they diagnosed following diseases, common cold, tonsillitis, pneumonia or any other possible respiratory infectious diseases.
- severity of postoperative sore throat (POST) [When arriving at postanesthesia care unit (PACU) and thereafter 2, 4, and 24 hours after the surgery]
The severity of POST was evaluated on a 4-point-scale : 0, no sore throat; 1, mild sore throat (complained of sore throat only upon inquiry); 2, moderate sore throat (complained of sore throat on his/her own); 3, severe sore throat (change of voice or hoarseness, associated with throat pain)
Eligibility Criteria
Criteria
Inclusion Criteria:
- patients aged between 20-80 years who were scheduled for surgery under general anesthesia requiring orotracheal intubation
Exclusion Criteria:
-
history of gastroesophageal reflux disease (GERD)
-
congenital or acquired abnormalities of the upper airway such as tumor, polyp, trauma, abscess, inflammation, infection, or foreign bodies
-
previous airway surgery; increased risk of aspiration
-
coagulation disorders
-
previous history of difficult intubation or conditions with expected difficult airway including Mallampati classification ≥ 3 or thyromental distance < 6.5 cm
-
Using the other intubation devices beyond the direct laryngoscopy such as lighted stylet or fiberoptic bronchoscopy
-
symptoms of sore throat or upper respiratory tract infection
-
expected to place nasogastric tube during perioperative period
-
requiring nasotracheal intubation
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Seoul National University Hospital | Seoul | Korea, Republic of |
Sponsors and Collaborators
- Seoul National University Hospital
Investigators
- Study Chair: Jeong-Hwa Seo, Associate professor, Seoul National University Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- JHSeo_Saline