Fat Burning After a Meal

Sponsor

USDA Grand Forks Human Nutrition Research Center (U.S. Fed)

Overall Status

Completed

CT.gov ID

NCT02211599

Collaborator

(none)

Enrollment

Location

Arms

Actual Duration (Months)

1.5

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of the study is to determine how adding a carbohydrate beverage to a meal with different protein levels affects the rate at which one's body burns fats, sugars, and proteins.

Condition or Disease	Intervention/Treatment	Phase
Postprandial Effect of Carbohydrate Beverage Consumption	Other: 15% protein Other: 30% protein Other: Sweetened beverage	N/A

Study Design

Study Type:

Interventional

Actual Enrollment :

29 participants

Allocation:

Randomized

Intervention Model:

Crossover Assignment

Masking:

Double (Participant, Investigator)

Primary Purpose:

Other

Official Title:

Post-Prandial Substrate Utilization in Response to the Inclusion of Sweetened Beverage to Meals With Different Levels of Protein Content

Actual Study Start Date :

Nov 1, 2014

Actual Primary Completion Date :

Jun 1, 2016

Actual Study Completion Date :

Jun 1, 2016

Arms and Interventions

Arm	Intervention/Treatment
Experimental: 15% protein meal and sweetened beverage Breakfast and lunch will each contain 15% protein. A sweetened flavored beverage will be served with each meal; one drink will be sweetened with sugar and the other with sucralose (a non-nutritive sweetener). Order will be randomized.	Other: 15% protein Meal to provide 15%en from protein. Other: Sweetened beverage Beverage sweetened with either sugar (sucrose) or sucralose (non-nutritive sweetener).
Experimental: 30% protein meal and sweetened beverage Breakfast and lunch will each contain 30% protein. A sweetened flavored beverage will be served with each meal; one drink will be sweetened with sugar and the other with sucralose (a non-nutritive sweetener). Order will be randomized.	Other: 30% protein Meal to provide 30%en from protein. Other: Sweetened beverage Beverage sweetened with either sugar (sucrose) or sucralose (non-nutritive sweetener).

Arm

Intervention/Treatment

Experimental: 15% protein meal and sweetened beverage

Breakfast and lunch will each contain 15% protein. A sweetened flavored beverage will be served with each meal; one drink will be sweetened with sugar and the other with sucralose (a non-nutritive sweetener). Order will be randomized.

Other: 15% protein

Meal to provide 15%en from protein.

Other: Sweetened beverage

Beverage sweetened with either sugar (sucrose) or sucralose (non-nutritive sweetener).

Experimental: 30% protein meal and sweetened beverage

Breakfast and lunch will each contain 30% protein. A sweetened flavored beverage will be served with each meal; one drink will be sweetened with sugar and the other with sucralose (a non-nutritive sweetener). Order will be randomized.

Other: 30% protein

Meal to provide 30%en from protein.

Other: Sweetened beverage

Beverage sweetened with either sugar (sucrose) or sucralose (non-nutritive sweetener).

Outcome Measures

Primary Outcome Measures

Postprandial lipid oxidation rate [4 hours after meal consumption]

Secondary Outcome Measures

Energy expenditure measured by postprandial thermogenesis [4 hours after meal consumption]
Postprandial protein oxidation [4 hours after meal consumption]
Postprandial carbohydrate oxidation [4 hours after meal consumption]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 65 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

BMI less than 25 kg/m2
ability to sign the consent form
availability of transportation

Exclusion Criteria:

percent body fat greater than or equal to 25% for males and 35% for females
allergies to any study foods
more than a 10% change in body weight within the past 2 months
current or planned pregnancy
lactation
metabolic illness/disease(s)
active cancer or in short-term remission (less than 3 years)
infectious diseases
alcohol or drug abuse
tobacco use
presence of acute illness
taking medications known to affect energy expenditure and appetite

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	USDA Grand Forks Human Nutrition Research Center	Grand Forks	North Dakota	United States	58203

Sponsors and Collaborators

USDA Grand Forks Human Nutrition Research Center

Investigators

Principal Investigator: Shanon Casperson, PhD, USDA Grand Forks Human Nutrition Research Center
Principal Investigator: James Roemmich, PhD, USDA Grand Forks Human Nutrition Research Center