Effects of Ritalin on Postural Stability of Old Adults

Sponsor

Soroka University Medical Center (Other)

Overall Status

Completed

CT.gov ID

NCT00817960

Collaborator

(none)

Enrollment

Location

Arm

Duration (Months)

2.7

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Experimental design overview The proposed project is a prospective experimental study design. independent old adults(age 65 years old and older) who do not suffer from balance problems willing to participate in the study will be tested with well-established measuring techniques of Balance control before and 2 hours after taking of Methylphenidate (Ritalin) in the movement and Rehabilitation Laboratory at BGU. An automated algorithm will be used to extract standardized stabilogram-diffusion parameters from each of the COP data sets collected during quiet standing. These parameters include diffusion coefficients, critical displacement, critical time and scaling exponents for both lateral and anterior-posterior sway directions (Collins & De Luca, 1993). For each of the conditions (before and 1 hour after the use of Ritalin) in three task conditions single task; dual task (concentrating and identifying specific music); and just Listening to a relaxing music. Participants will be required to stand on the platform 10 times for 30 s. For each trial, they will be instructed to sway as little as possible.

Condition or Disease	Intervention/Treatment	Phase
Postural Imbalance	Drug: Methylphenidate	N/A

Study Design

Study Type:

Interventional

Actual Enrollment :

30 participants

Allocation:

Randomized

Intervention Model:

Parallel Assignment

Masking:

Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Primary Purpose:

Treatment

Official Title:

Effects of Methylphenidate on Postural Stability of Old Adults Under Single and Dual Task Conditions.

Study Start Date :

Jul 1, 2011

Actual Primary Completion Date :

Jan 1, 2012

Actual Study Completion Date :

Jun 1, 2012

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Methylphenidate	Drug: Methylphenidate The effect of ritalin on postural stability of old adults (65 years old and over) will be measured using RCT study design

Arm

Intervention/Treatment

Experimental: Methylphenidate

Drug: Methylphenidate

The effect of ritalin on postural stability of old adults (65 years old and over) will be measured using RCT study design

Outcome Measures

Primary Outcome Measures

Postural sway measures [Time 1: pre test' and hour later time 2: post testinng proceedure]

Eligibility Criteria

Criteria

Ages Eligible for Study:

65 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Age 65 years old and older
independent elderly adults
do not suffer from balance prblems
minimental score 24 and above

Exclusion Criteria:

old adults who suffer from neurological disease or stroke
old adults who suffer from psychiatric state
old adults who suffer from orthopedic condition (1/2 a year after a fracture in the lower limb)
old adults who suffer from heart conditions
old adults who suffer from blindness

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	SorokaUMC	Beer-Sheva		Israel	84105

Sponsors and Collaborators

Soroka University Medical Center

Investigators

Principal Investigator: Itshak Melzer, PhD, Ben-gurion University of the Negev, Beer-Sheva, Israel
Study Chair: Zmir Shorer, m, Soroka University Medical Centar
Study Director: Yan Press, MD, Soroka University Medical Center