Practice Patterns Among Gynecologic Oncologists on Tumor Genetic Testing in Endometrial Cancer

Sponsor
Wake Forest University Health Sciences (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05877404
Collaborator
(none)
360
1
4
89.8

Study Details

Study Description

Brief Summary

In order to formulate strategies to improve adherence to best practice guidelines, as well as utilization of novel therapies, investigators must understand current practice patterns surrounding tumor genetic testing in endometrial cancer. The aim is to survey a representative sample of gynecologic oncologists who belong to the society of gynecologic oncology, via an email survey, to better understand current practices surrounding tumor genetic testing as well as determine if there have been any changes to practice since the publication of recent trials on the use of immune-checkpoint inhibitors in endometrial cancer.

Condition or Disease Intervention/Treatment Phase
  • Other: Surveys

Detailed Description

Primary Objective: Proportion of physicians reporting the use of different tumor genetic testing strategies among newly diagnosed endometrial cancer patients.

Secondary Objectives:
  • Explore the use of informed consent in tumor genetic testing in endometrial cancer

  • Explore clinician confidence in utilizing tumor genetic testing to guide treatment decisions.

  • Explore the impact of recent publications regarding immunotherapy on the use of tumor genetic testing in endometrial cancer.

Study Design

Study Type:
Observational
Anticipated Enrollment :
360 participants
Observational Model:
Other
Time Perspective:
Prospective
Official Title:
Practice Patterns Among Gynecologic Oncologists on Tumor Genetic Testing in Endometrial Cancer
Anticipated Study Start Date :
Aug 1, 2023
Anticipated Primary Completion Date :
Dec 1, 2023
Anticipated Study Completion Date :
Dec 1, 2023

Arms and Interventions

Arm Intervention/Treatment
Gynecologic Oncologists

Gynecologic Oncologists and gynecologic oncology fellows-in-training from around the world, who are members of the Society of Gynecologic Oncology (SGO).

Other: Surveys
Survey on practice patterns surrounding tumor genetic testing in endometrial cancer.

Outcome Measures

Primary Outcome Measures

  1. Percentage of providers reporting the use of different tumor genetic testing strategies among newly diagnosed endometrial cancer patients [4 months]

    The primary outcome is to estimate the percentage of providers who report the use of different tumor testing strategies. Investigators will calculate the frequencies of responses to each testing strategy and then compare the percentage of physicians who choose different strategies, using a chi-square or Fisher's exact test.

Secondary Outcome Measures

  1. Frequency of providers using different strategies of informed consent in tumor genetic testing in endometrial cancer [4 months]

    Investigators will calculate the number of frequencies of different tumor testing informed consent strategies among physicians.

  2. Number of providers reporting confidence in utilizing tumor genetic testing to guide treatment decisions [4 months]

    Investigators will calculate the number of providers who are very confident, moderately confident, a little confident or not at all confident in their ability to explain tumor testing strategies and results.

  3. Number of providers who change their counseling or testing strategies for endometrial cancer [4 months]

    Investigators will compare the number of providers who have changed their counseling or testing strategy based on their familiarity with recent publications regarding immune-checkpoint inhibitors in advanced and recurrent endometrial cancer using a chi-square or Fisher's exact test.

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Member of the Society of Gynecologic Oncology

  • Gynecologic Oncologist or Gynecologic Oncology Fellow-in-Training

Contacts and Locations

Locations

Site City State Country Postal Code
1 Wake Forest Baptist Comprehensive Cancer Center Winston-Salem North Carolina United States 27157

Sponsors and Collaborators

  • Wake Forest University Health Sciences

Investigators

  • Principal Investigator: Kathryn Weaver, PhD, MPH, Wake Forest Baptist Comprehensive Cancer Center

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Wake Forest University Health Sciences
ClinicalTrials.gov Identifier:
NCT05877404
Other Study ID Numbers:
  • IRB00097221
  • WFBCCC 99323
First Posted:
May 26, 2023
Last Update Posted:
May 30, 2023
Last Verified:
May 1, 2023
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Wake Forest University Health Sciences
Additional relevant MeSH terms:

Study Results

No Results Posted as of May 30, 2023