Can Pregnancy be Predicted According to ATR-FTIR Spectrophotometry of Incubation Medium of Embryos in IVF
Sponsor
Hillel Yaffe Medical Center (Other)
Overall Status
Recruiting
CT.gov ID
NCT03317418
Collaborator
(none)
100
1
72
1.4
Study Details
Study Description
Brief Summary
The aim of this study is to examine the variability of culture media composition based on the ATR-FTIR (Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy) technique on the day of embryo transfer/vitrification. In addition, the study will explore whether variations detected in the culture medium can be linked to embryo quality and the chances of achieving pregnancy.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Anticipated Enrollment
:
100 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Can Pregnancy be Predicted According to ATR-FTIR Spectrophotometry of Incubation Medium of Embryos in IVF
Actual Study Start Date
:
Nov 1, 2017
Anticipated Primary Completion Date
:
Nov 1, 2023
Anticipated Study Completion Date
:
Nov 1, 2023
Outcome Measures
Primary Outcome Measures
- Spectrometry in embryo culture media [One year]
Definition of spectrometry in embryo culture media
- Embryo quality [One year]
The spectrometry results will be linked to embryo quality through the linkage between spectrometry results as indicated on Absorbance Graph and embryo quality judged by accepted criteria
Secondary Outcome Measures
- Cycle outcomes [One year]
Prediction of pregnancy rates as linked to the spectrometry results of the culture media
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
to 45 Years
Sexes Eligible for Study:
Female
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
- Women undergoing IVF treatments with at least 4 embryos
Exclusion Criteria:
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Hillel Yaffe Medical Center | H̀±adera | Israel | 38100 |
Sponsors and Collaborators
- Hillel Yaffe Medical Center
Investigators
- Principal Investigator: Einat Shalom Paz, MD, Hillel Yaffe Medical Center
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Hillel Yaffe Medical Center
ClinicalTrials.gov Identifier:
NCT03317418
Other Study ID Numbers:
- HYMC-0071-17
First Posted:
Oct 23, 2017
Last Update Posted:
Jun 23, 2022
Last Verified:
Jun 1, 2022
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: