The Presence and Role of Zygomatic-temporal Neuroma Triggering Cluster Headache

Sponsor
Corona Doctors Medical Clinics, Inc. (Other)
Overall Status
Recruiting
CT.gov ID
NCT04845451
Collaborator
(none)
10
1
5.5
1.8

Study Details

Study Description

Brief Summary

Role of a neuroma of zygomatic-temporal in triggering of a cluster headache. Exploratory diagnosis, resection, and pathological examination of tumor anticipated

.

Condition or Disease Intervention/Treatment Phase
  • Other: Minimal surgical exploration for a neuroma

Detailed Description

An anatomical coordinated communication of a Cluster Circuit turned on by Zygomatico-Temporal neuroma, a malicious possibly nontraumatic, neoplastic tissue coding and decoding itself upon autonomic release of neurotransmitter(s). Exhaustion of neurotransmitter synthesis turns out the explosions of pain-symptoms off.

Poor attention to the characterization of a peripheral neuroma of trigeminal nerve branch deranged attention to central(CNS) characterization of Cluster Symptoms.

This study based on our experimental results of minimal surgical procedure to explore, diagnose and resect a Zygomatico-Temporal neuroma in the temple of patients suffering from EpisodicChronic, Cluster Headache-ECCH. The goal is to light on this speculation in a novel analysis of events to put an end to devastating catastrophic headaches. Detailed anatomical components loci of the autonomic symptoms in the cluster headache reveal the presence of an electrical neural circuit.

The extracranial circuit components of ECCH reflects the anatomical nerve components participating reflection of the single circumscribed symptom:

  1. Zygomatico-Temporal-neuroma

  2. Zygomatic nerve V-II

  3. Intraorbital communicants rami

  4. Lacrimal nerve V-I

  5. Ophthalmic nerve Intraorbital routing, supraorbital nerves, the upper eyelid, the conjunctiva and cornea of the eye, the nose (including the tip of the nose, except alae nasi), the nasal mucosa, the frontal sinuses. V-I

  6. Optic nerve via ophthalmic nerve routing and electricity propagation.

  7. Pterygopalatine ganglion as peripheral and CNS coordinator center.

An intracranial CNS reaction follows in response to the perception of pain materialized in neuroimaging during the activity of ECCH.

Study Design

Study Type:
Observational
Anticipated Enrollment :
10 participants
Observational Model:
Case-Only
Time Perspective:
Prospective
Official Title:
The Presence and Role of Zygomatic-temporal Neuroma Triggering Cluster Headache: Resection of a Neuroma in the Long-term Resolution of Trigeminal Cluster Symptoms
Actual Study Start Date :
Apr 9, 2021
Anticipated Primary Completion Date :
Jun 10, 2021
Anticipated Study Completion Date :
Sep 23, 2021

Outcome Measures

Primary Outcome Measures

  1. Presence of Neuroma [6 months]

    Zygomaticotemporal neuroma as trigger of Episodic and Chronic Cluster headache

  2. Resolution of Cluster Headache attacks [6 months]

    Resection of a ZT-neuroma may eradicate Cluster Headache trigger

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No

Inclusion Criteria: Episodic Chronic Cluster Headaches -

Exclusion Criteria:

Malignant hypertension, Brain tumors, brain vascular abnormalities

-

Contacts and Locations

Locations

Site City State Country Postal Code
1 Corona Doctors Medical Clinics Inc Corona California United States 92879

Sponsors and Collaborators

  • Corona Doctors Medical Clinics, Inc.

Investigators

  • Principal Investigator: Faro T Owiesy, M.D., CORONA DOCTORS MEDICAL CLINICS

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
FARO T. OWIESY, M.D, Faro Ted Owiesy, M.D., Corona Doctors Medical Clinics, Inc.
ClinicalTrials.gov Identifier:
NCT04845451
Other Study ID Numbers:
  • CoronaDMC
First Posted:
Apr 15, 2021
Last Update Posted:
Apr 15, 2021
Last Verified:
Apr 1, 2021
Individual Participant Data (IPD) Sharing Statement:
Yes
Plan to Share IPD:
Yes
Keywords provided by FARO T. OWIESY, M.D, Faro Ted Owiesy, M.D., Corona Doctors Medical Clinics, Inc.
Additional relevant MeSH terms:

Study Results

No Results Posted as of Apr 15, 2021