SERUM MYOCINE BINDING PROTEIN C LEVEL and PRETERM DELİVERY

Sponsor

Gaziosmanpasa Research and Education Hospital (Other)

Overall Status

Recruiting

CT.gov ID

NCT05513768

Collaborator

(none)

Enrollment

Location

Arms

Anticipated Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

IT WAS AIMED TO EVALUATE IF MBPC CAN BE USED IN PREDICTION OF EARLY BIRTH. TAKING THE FIRST TRIMESTER FROM PREGNANCY WAS STORED UNTIL THE TIMING OF DELIVERY.THE PARTICIPANTS WERE SEPARATED INTO TWO GROUPS ACCORDING TO THE TIME OF BIRTH, EARLY AND TIMELY.

SERUM MBPC LEVELS BETWEEN TWO GROUPS EVALUATED.

Condition or Disease	Intervention/Treatment	Phase
Preterm	Diagnostic Test: level of myosin binding protein c in serum	N/A

Detailed Description

SERUM MBPC LEVELS BETWEEN TWO GROUPS EVALUATED.A TOTAL OF 90 WOMEN WERE PLANNED TO INCLUDE 45 STUDY 45 CONTROL GROUP IN THE STUDY.

Study Design

Study Type:

Interventional

Anticipated Enrollment :

90 participants

Allocation:

Non-Randomized

Intervention Model:

Parallel Assignment

Masking:

None (Open Label)

Primary Purpose:

Diagnostic

Official Title:

Can First Trimester Serum Mbpc Level Predict Preterm Birth?

Actual Study Start Date :

Jan 1, 2022

Anticipated Primary Completion Date :

Sep 30, 2022

Anticipated Study Completion Date :

Oct 1, 2022

Arms and Interventions

Arm	Intervention/Treatment
Other: women who gave birth prematurely women who had serum taken in the first trimester and gave birth earlier than 37 weeks according to the time of delivery	Diagnostic Test: level of myosin binding protein c in serum Serum samples will be taken from the participants in the first trimester, transferred to eppendorf tubes after appropriate procedures, and stored at -80 degrees until the time of deliveryParticipants will be divided into two groups according to the timing of birthThe first group is those who gave birth earlier than 37 weeks those who gave birth on time in the other group The mbpc levels will be looked at and compared.
Other: those who gave birth on time women who have had serum taken in the first trimester, stored and delivered on time	Diagnostic Test: level of myosin binding protein c in serum Serum samples will be taken from the participants in the first trimester, transferred to eppendorf tubes after appropriate procedures, and stored at -80 degrees until the time of deliveryParticipants will be divided into two groups according to the timing of birthThe first group is those who gave birth earlier than 37 weeks those who gave birth on time in the other group The mbpc levels will be looked at and compared.

Arm

Intervention/Treatment

Other: women who gave birth prematurely

women who had serum taken in the first trimester and gave birth earlier than 37 weeks according to the time of delivery

Diagnostic Test: level of myosin binding protein c in serum

Serum samples will be taken from the participants in the first trimester, transferred to eppendorf tubes after appropriate procedures, and stored at -80 degrees until the time of deliveryParticipants will be divided into two groups according to the timing of birthThe first group is those who gave birth earlier than 37 weeks those who gave birth on time in the other group The mbpc levels will be looked at and compared.

Other: those who gave birth on time

women who have had serum taken in the first trimester, stored and delivered on time

Diagnostic Test: level of myosin binding protein c in serum

Outcome Measures

Primary Outcome Measures

detection of prediction value of serum mbpc levels in preterm delivery [10 mounths]
identifying prediction value of first trmester serum mbpc levels by comparing by serum levels of mbpc in groups

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 40 Years

Sexes Eligible for Study:

Female

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

being pregnant in the first trimester
be between 18-40 years old

Exclusion Criteria:

no history of preterm birth
being pregnant with assisted reproductive techniques
having a multiple pregnancy
have cervical insufficiency

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Gaziosmanpasa Training and Research Hospital	Istanbul	Gaziosmanpaşa	Turkey	32225

Sponsors and Collaborators

Gaziosmanpasa Research and Education Hospital

Investigators

Principal Investigator: elif yıldız, Gaziosmanpasa Research and Education Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Gaziosmanpasa Research and Education Hospital

ClinicalTrials.gov Identifier:

NCT05513768

Other Study ID Numbers:

GaziosmanpasaTREHKHD

First Posted:

Aug 24, 2022

Last Update Posted:

Aug 24, 2022

Last Verified:

Aug 1, 2022

Individual Participant Data (IPD) Sharing Statement:

Plan to Share IPD:

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Gaziosmanpasa Research and Education Hospital

PRETERM DELİVERY, MBPC,

Additional relevant MeSH terms:

Premature Birth

Protein C

Study Results

No Results Posted as of Aug 24, 2022