Prevalence of Anemia and Growth Assessment in Acute Gastroenteritis

Sponsor
Assiut University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT06038305
Collaborator
(none)
297
13

Study Details

Study Description

Brief Summary

  1. Assessment of the growth parameters in infants admitted with acute gastroenteritis.

  2. Determine the prevalence of anemia in infants admitted with acute gastroenteritis.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Gastroenteritis is inflammation of the stomach, small intestine, or large intestine, leading to a combination of abdominal pain, cramping, nausea, vomiting, and diarrhea. Acute gastroenteritis usually lasts fewer than 14 days. Worldwide, gastroenteritis affects 3 to 5 billion children each year. Up to 40% of children aged less than 5 years with diarrhea are hospitalized with rotavirus. Also, some microorganisms have been found predominantly in resource-constrained nations, including Shigella spp, Vibrio cholerae, and the protozoan infections. Malnutrition, immunosuppression, young age, and an increase in the preceding diarrhea burdens are risk factors for the development of persistent diarrhea. A substantial proportion of global malnutrition is due to impaired intestinal absorptive function resulting from multiple and repeated enteric infections. These include recurrent acute infections as well as persistent infections, even those without overt liquid diarrhea.

    Child growth is internationally recognized as the best global indicator of physical well-being in children because poor feeding practices-both in quantity and quality-and infections, or more often a combination of the two, are major factors that affect physical growth and mental development in children. The most important measurements needed for growth assessment are recumbent length or height, weight and head circumference. These fundamental anthropometric measures should be obtained and interpreted at each well child visit, and are typically sufficient for growth assessment.

    In this study, the prevalence of anemia and growth of infants admitted with acute gastroenteritis at Assiut University Children Hospital will be assessed. Anemia is a global public health problem, with important consequences for human health and the social and economic development of each nation. It results from single or multiple causes that act simultaneously, influencing children's health, their cognitive and physical development, and immunity, increasing the risk of infections and infant mortality.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    297 participants
    Observational Model:
    Case-Only
    Time Perspective:
    Cross-Sectional
    Official Title:
    Prevalence of Anemia and Growth Assessment of Infants Admitted With Acute Gastroenteritis in Assiut University Children Hospital
    Anticipated Study Start Date :
    Jan 1, 2024
    Anticipated Primary Completion Date :
    Jan 1, 2025
    Anticipated Study Completion Date :
    Feb 1, 2025

    Outcome Measures

    Primary Outcome Measures

    1. Determine association between anemia and acute gastroenteritis in infants and children. [baseline]

      assess anemia in children with acute gastroenteritis and if anemia affect severity of acute gastroenteritis

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    1 Month to 2 Years
    Sexes Eligible for Study:
    All
    Inclusion Criteria:
    • Infants with acute gastroenteritis.

    • Infants aged from 1 month and up to 2 years.

    Exclusion Criteria:
    • Infants aged less than 1 month and more than 2 years.

    • Infants with persistent and chronic diarrhea.

    • Infants with acute gastroenteritis in association with chronic disease

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • Assiut University

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Gehad Ali Sayed, Resident physician, Family Medicine department, Assiut University
    ClinicalTrials.gov Identifier:
    NCT06038305
    Other Study ID Numbers:
    • anemia and growth in AGE
    First Posted:
    Sep 14, 2023
    Last Update Posted:
    Sep 15, 2023
    Last Verified:
    Sep 1, 2023
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Sep 15, 2023