Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-Thalassemia
Sponsor
Hillel Yaffe Medical Center (Other)
Overall Status
Unknown status
CT.gov ID
NCT01092169
Collaborator
(none)
Study Details
Study Description
Brief Summary
Sickle cell nephropathy is a known complication of sickle cell anemia (SCA) manifested by increase in glomerular filtration rate (glomerular hyperfiltration) and results in proteinuria and chronic renal failure.
Our goal is to examine the prevalence of proteinuria and microalbuminuria as an early predictive factor of glomerular injury, among young people who suffer from SCA as well as those who suffer from combined sickle cell/beta-thalassemia.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Observational Model:
Cohort
Time Perspective:
Cross-Sectional
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Sickle cell beta
|
Other: No intervention
|
Outcome Measures
Primary Outcome Measures
Eligibility Criteria
Criteria
Ages Eligible for Study:
N/A
to 25 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
Patients diagnosed with sickle cell anemia
-
Patients diagnosed with combined sickle cell anemia/beta-thalassemia
Exclusion Criteria:
-
Diabetes mellitus
-
Hypertension
-
Reduced renal mass (single kidney)
-
Overweight
-
History of UTIs
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Hillel Yaffe Medical Center
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT01092169
Other Study ID Numbers:
- 64/2009
First Posted:
Mar 24, 2010
Last Update Posted:
Mar 24, 2010
Last Verified:
Mar 1, 2010