Prevalence of NCD Risk Factors in Kazakhstan

Sponsor
Asfendiyarov Kazakh National Medical University (Other)
Overall Status
Completed
CT.gov ID
NCT05122832
Collaborator
(none)
20,400
1
9.9
2062.9

Study Details

Study Description

Brief Summary

This is a cross-sectional study that aims to study the prevalence of risk factors of noncommunicable diseases in people aged 18 to 69 years using the standardized and adopted STEPS questionnaire in the Republic of Kazakhstan.

Condition or Disease Intervention/Treatment Phase
  • Diagnostic Test: Blood test
  • Diagnostic Test: STEPwise Approach to NCD Risk Factor Surveillance (STEPS)
  • Diagnostic Test: Spirometry

Detailed Description

The WHO STEPwise Approach to NCD Risk Factor Surveillance (STEPS) is a simple, standardized method for collecting, analysing and disseminating data on key NCD risk factors in countries. The survey instrument covers key behavioral risk factors: tobacco use, alcohol consumption, physical activity, unhealthy diet, as well as key biological risk factors: overweight and obesity, raised blood pressure, raised blood glucose, and abnormal blood lipids.

Study Design

Study Type:
Observational
Actual Enrollment :
20400 participants
Observational Model:
Other
Time Perspective:
Cross-Sectional
Official Title:
Preventive and Personalized Medicine (2021-2023)
Actual Study Start Date :
Oct 23, 2021
Actual Primary Completion Date :
Aug 20, 2022
Actual Study Completion Date :
Aug 20, 2022

Arms and Interventions

Arm Intervention/Treatment
The study Group

Population of Kazakhstan

Diagnostic Test: Blood test
Glucose Glycosylated hemoglobin Triglycerides Total cholesterol HDL Cholesterol LDL Cholesterol Creatinine COVID-19 Antibody IgM to N protein SARS-Cov-2 (Abbott) COVID-19 Antibody IgG to N protein SARS-Cov-2 (Abbott)

Diagnostic Test: STEPwise Approach to NCD Risk Factor Surveillance (STEPS)
The WHO STEPwise Approach to NCD Risk Factor Surveillance (STEPS) is a simple, standardized method for collecting, analysing and disseminating data on key NCD risk factors in countries. The survey instrument covers key behavioral risk factors: tobacco use, alcohol consumption, physical activity, unhealthy diet, as well as key biological risk factors: overweight and obesity, raised blood pressure, raised blood glucose, and abnormal blood lipids. Through the use of expanded modules, the survey instrument can be expanded to cover a range of topics beyond these risk factors, such as oral health, sexual health and road safety.

Diagnostic Test: Spirometry
Spirometry is a common office test used to assess how well your lungs work by measuring how much air you inhale, how much you exhale and how quickly you exhale.

Outcome Measures

Primary Outcome Measures

  1. tobacco use [1 year]

    currently smoke tobacco, currently smoke tobacco daily, age started smoking, daily smokers smoking manufactured cigarettes

  2. alcohol consumption [1 year]

    lifetime abstainers, past 12 month abstainers, currently drink (drank alcohol in the past 30 days), heavy episodic drinking (6 or more drinks on any occasion in the past 30 days).

  3. physical activity [1 year]

    insufficient physical activity (defined as < 150 minutes of moderate-intensity activity per week, or equivalent), physical activity on average per day (minutes), not engaging in vigorous activity.

  4. unhealthy diet [1 year]

    days fruit consumed in a typical week, servings of fruit consumed on average per day, days vegetables consumed in a typical week, servings of vegetables consumed on average per day, less than 5 servings of fruit and/or vegetables on average per day, always or often add salt or salty sauce to their food before eating or as they are eating, always or often eat processed foods high in salt.

  5. BMI [1 year]

    overweight (BMI ≥ 25 kg/m2), obese (BMI ≥ 30 kg/m2), normal weight

  6. raised blood pressure [1 year]

    systolic blood pressure - SBP (mmHg), including those currently on medication for raised BP, diastolic blood pressure - DBP (mmHg), including those currently on medication for raised BP, raised BP (SBP ≥ 140 and/or DBP ≥ 90 mmHg or currently on medication for raised BP), raised BP (SBP ≥ 140 and/or DBP ≥ 90 mmHg or currently on medication for raised BP) who are not currently on medication for raised BP.

  7. raised blood glucose [1 year]

    fasting blood glucose, including those currently on medication for raised blood glucose, impaired fasting glycaemia (plasma venous value ≥6.1 mmol/L (110 mg/dl) and <7.0 mmol/L (126 mg/dl)), raised fasting blood glucose (plasma venous value ≥ 7.0 mmol/L (126 mg/dl)) or currently on medication for raised blood glucose.

  8. abnormal blood lipids [1 year]

    total blood cholesterol, including those currently on medication for raised cholesterol, raised total cholesterol,

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 69 Years
Sexes Eligible for Study:
All
Inclusion Criteria:
  • Age Limits 18-69 years

Contacts and Locations

Locations

Site City State Country Postal Code
1 Kazakhstan Almaty Kazakhstan 050020

Sponsors and Collaborators

  • Asfendiyarov Kazakh National Medical University

Investigators

  • Principal Investigator: Timur M Saliev, S.D. Asfendiyarov Kazakh National Medical University
  • Study Chair: Ildar R Fakhradiyev, PhD, S.D. Asfendiyarov Kazakh National Medical University
  • Study Director: Mukhtar B Kulimbet, MD/MSc, S.D. Asfendiyarov Kazakh National Medical University
  • Principal Investigator: Zhumaly A Kauyzbay, PhD, AP, Joint Stock Company - South Kazakhstan Medical Academy
  • Principal Investigator: Samat S Saparbayev, PhD, West Kazakhstan Marat Ospanov Medical University
  • Principal Investigator: Alma U Nurtazina, MD/PhD, NCJSC Semey Medical University
  • Principal Investigator: Bayan A Ainabekova, MD/DMSc, NCJSC Astana Medical University
  • Principal Investigator: Anar A Turmukhambetova, DMSc, NCJSC Karaganda Medical University
  • Principal Investigator: Maksut K Kulzhanov, DMSc, Kazakhstan's Medical University "KSPH"

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Ildar Fakhradiyev, Head of the Laboratory of Experimental Medicine, Asfendiyarov Kazakh National Medical University
ClinicalTrials.gov Identifier:
NCT05122832
Other Study ID Numbers:
  • 1197
First Posted:
Nov 17, 2021
Last Update Posted:
Aug 23, 2022
Last Verified:
Aug 1, 2022
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Aug 23, 2022