Prevalence of Non-alcoholic Fatty Liver Disease in Patients With Chronic Kidney Disease in Assiut
Study Details
Study Description
Brief Summary
The goal of this observational study is to detect the prevalence of NAFLD in CKD patients
The main question[s] it aims to answer are:
-
[question 1] prevalence of NAFLD in CKD patients.
-
[question 2] the relationship between NAFLD and CKD.
Detailed Description
The goal of this observational study is to detect the prevalence of NAFLD in CKD patients
The main question[s] it aims to answer are:
-
[question 1] prevalence of NAFLD in CKD patients.
-
[question 2] the relationship between NAFLD and CKD.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| CKD patients CKD patient who are not DM are investigated for the presence of NAFLD |
|
| normal control group normal population are investigated to know the prevalence of NAFLD in contrast to patients with CKD. |
Outcome Measures
Primary Outcome Measures
- abdominal ultrasound [1 year]
assessment of Liver regarding fatty liver disease by Ultrasound.
- liver enzymes [1 year]
participants will undergo assessment of liver enzymes (AST and ALT) and results will be reporeted in a table.
- Fibroscan [1 year]
participants will undergo fibroscanning of the liver to assess NAFLD and results will be reported in a table.
- BUN, Cr level and estimated GFR [1 year]
participants will be assessed regarding BUN, CR and estimated GFR to confirm and follow up CKD patients involved in the study.
- Lipid Profile [1 year]
participants will be assessed regarding Cholesterol level, Triglycerides, HDL and LDL. results will be reported in a table
- Complete Blood Picture (WBCs, HB, Patelets [1 year]
total leucocytic count Hemoglobin level and platelet count will be assessed in our patients and will be reported in a table
- serum Uric Acid [1 year]
serum uric acid will be assessed and reported in our patients
Secondary Outcome Measures
- Waist Circumference [1 year]
waist circumference measurement.
- Body Mass Index [1 year]
BMI will also be calculated.
Eligibility Criteria
Criteria
Inclusion Criteria:
- CKD patients
Exclusion Criteria:
-
HCV and HBV Positive patients
-
Alcoholics
-
patient on Hemodialysis
-
patients with wilson disease
-
patients with alpha one antitrypsin deficiency
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Muhammad Ameen Abdelrady Abdelaziz
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- NAFLD and CKD