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Prevelance of Keratoconus

Sponsor
Assiut University (Other)
Overall Status
Unknown status
CT.gov ID
NCT04092426
Collaborator
(none)
300
Enrollment
24
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

Keratoconus is a degenerative disease entity characterized by conical shape ectasia of the cornea. progressive conical deformation of the cornea leads to substantial astigmatism. Patients who are at an advanced stage of ectasia are often led to corneal transplant or other treatments, which essentially aim at correcting the refractive error and not in treating the ectasia. The top of the protruding cone that corneal configuration may be close to the visual axis or below and nasal of that. The disease manifests during adolescence, followed by slow progressive course, although it is possible to stabilize anytime. In 85% of cases both eyes are affected, but the severity of the attack can present significant asymmetry.

Condition or Disease Intervention/Treatment Phase
  • Other: opthalmologic examination

Detailed Description

Often in keratoconus a positive family history is present. Prevelance of keratoconus varies greatly worldwide.The reported prevalence of keratoconus varies widely depending upon the geographic location, diagnostic criteria used, and the cohort of patients selected. Environmental factors may contribute to the wide variation in prevalence.

the Middle East have higher prevalence than locations with cooler climates and less sunshine

Study Design

Study Type:
Observational
Anticipated Enrollment :
300 participants
Observational Model:
Case-Only
Time Perspective:
Prospective
Official Title:
Prevelance of Keratoconus in Individuals Attending Refreactive Surgery Centers in Assiut
Anticipated Study Start Date :
Oct 1, 2019
Anticipated Primary Completion Date :
Oct 1, 2020
Anticipated Study Completion Date :
Oct 1, 2021

Arms and Interventions

Arm Intervention/Treatment
patients with keratoconus

patients with keratoconus attending refractive surgery centers in Assiut will be subjected to the following :- Full history and clinical evaluation. collection of individual data ( residency , occupation , special habbit , chronic illness ) Analysis of results to assess prevelance of keratoconus and its distribution geographically in Assiut

Other: opthalmologic examination
opthalmologic examination : Refraction Best corrected visual acuity Intraocular pressure Slit lamp examination

Outcome Measures

Primary Outcome Measures

  1. Prevalence of keratoconus in different areas in assiut [one year]

    Number of keratoconus cases detected areas in indivduals attending refractive surgery centers in Assiut

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
All
Inclusion Criteria:

  1. persons attending refractive surgery centers in Asssiut.

  2. patients found to have keratoconus are included , based on history , clinical examination and corneal topography

Exclusion criteria :

  1. patients not attending those refractive surgery centers.

  2. patients attending these centers but not diagnosed to be keratoconus .

  3. Pregnancy or breastfeeding

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Assiut University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
Mariam hamdy, principal investigator, Assiut University
ClinicalTrials.gov Identifier:
NCT04092426
Other Study ID Numbers:
  • keratoconus in assiut
First Posted:
Sep 17, 2019
Last Update Posted:
Sep 17, 2019
Last Verified:
Sep 1, 2019
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:
Keratoconus

Study Results

No Results Posted as of Sep 17, 2019