CCPW: Prevent Cancer- Greenville
Study Details
Study Description
Brief Summary
Prevent Cancer-Greenville was created to provide individuals with the opportunity to have their risk of developing cancer studied. Some individuals may be at a higher risk due to their personal lifestyle, family history and/or exposures. If subjects are found to be at high risk for developing a disease, they will be sent to a healthcare provider for further care.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
Participants' personal history, lifestyle behaviors and blood, urine, and cheek swab specimens will be used to detect changes or trends that might put them at risk for developing cancer. Some individuals may be at an above average risk of cancer due to lifestyle, family background, personal genetic makeup, or environmental exposures. This will be determined by a process called risk stratification. Risk stratification involves looking at all health-related aspects of a person, determining their individualized risk through screening, and educating them on measures to reduce potential for disease. Participants will complete a yearly health assessment which includes measurements for nutrition, activity, individual risk factors and body composition, including weight height and a special scale which measures fluid and fat.
Study Design
Outcome Measures
Primary Outcome Measures
- Assess changes in nutrition by nutrition questionnaire [Yearly follow up for 10 years]
Nutrition will be assessed yearly by a questionnaire based on nutrition recommendations from the American Institute for Cancer Research and the U.S. Department of Health and Human Services.
- Assess changes in physical activity by physical activity questionnaire [Yearly follow up for 10 years]
Physical activity will be assessed yearly a questionnaire based on physical activity recommendations from the U.S. Department of Health and Human Services.
- Assess changes in smoking habits [Yearly follow up for 10 years]
Participants will be educated on healthy lifestyle habits and smoking habits will be assessed yearly.
- Assess changes in alcohol use [Yearly follow up for 10 years]
Participants will be educated on healthy lifestyle habits and alcohol use will be assessed yearly.
- Assess hereditary risk through family history review [Yearly follow up for 10 years]
Each participant's family history will be reviewed to make recommendations for screening or genetic testing based on National Comprehensive Cancer Network guidelines.
- Assess lifetime breast cancer risk through the Tyrer-Cuzick version 8 breast risk evaluation tool [Yearly follow up for 10 years]
Participants' breast cancer risk will be assessed using the Tyrer-Cuzick breast cancer risk model. Participants will be referred to appropriate clinics if lifetime risk is greater than 20 percent.
- Assess 5- year breast cancer risk through the GAIL breast risk evaluation tool [Yearly follow up for 10 years]
Participants' breast cancer risk will be assessed using the National Cancer Institute's GAIL model. Participants will be referred to appropriate clinics if GAIL 5 year risk is greater than 1.7 percent.
- Early detection of malignancies through screening [Yearly follow up for 10 years]
Participants will be educated on screening recommendations by the American Cancer Society. Malignancies will be recorded yearly if found by recommended screenings.
- Assess changes in fat mass by SOZO measurements [Yearly follow up for 10 years]
Body composition will be assessed yearly by measurements taken from the SOZO device which uses bioimpedance spectroscopy to measure fat mass.
- Assess changes in muscle mass by SOZO measurements [Yearly follow up for 10 years]
Body composition will be assessed yearly by measurements taken from the SOZO device which uses bioimpedance spectroscopy to measure muscle mass.
Secondary Outcome Measures
- Assess changes in quality of life by the 5-level EuroQol-5D version (EQ-5D-5L) questionnaire [Yearly follow up for 10 years]
Quality of life will be assessed yearly by the EQ-5D-5L questionnaire. Participants' will self-report their health on a scale numbered 0-100. 100 means the best health you can imagine and 0 means the worst health you can imagine.
Eligibility Criteria
Criteria
Inclusion Criteria:
- 18 years or older
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Prisma Health-Upstate | Greenville | South Carolina | United States | 29605 |
Sponsors and Collaborators
- Prisma Health-Upstate
Investigators
- Principal Investigator: Larry Gluck, MD, Prisma Health-Upstate
Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
None provided.- Pro00077309