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Prognosis in Patients With Guillain-Barre Syndrome

Sponsor
First Affiliated Hospital of Wenzhou Medical University (Other)
Overall Status
Recruiting
CT.gov ID
NCT06032741
Collaborator
(none)
450
Enrollment
1
Location
145
Anticipated Duration (Months)
3.1
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The goal of this observational study is to explore significant indicators to predict the early prognosis and late prognosis in patients with Guillain-Barre syndrome.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    This is a multicenter study(approximately three) with over 450 subjects.Clinical data were collected by consulting the patient's electronic history. The data included demographic information, blood biochemical markers, clinical characteristics and electromyography. All participants provided their written informed consent to participate in this study.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    450 participants
    Observational Model:
    Cohort
    Time Perspective:
    Retrospective
    Official Title:
    Prognosis in Patients With Guillain-Barre Syndrome
    Actual Study Start Date :
    Jan 2, 2013
    Actual Primary Completion Date :
    Dec 1, 2022
    Anticipated Study Completion Date :
    Jan 31, 2025

    Arms and Interventions

    Arm Intervention/Treatment
    mechanical ventilation group

    Patients with Guillain-Barré Syndrome require mechanical ventilation during hospitalization
    no mechanical ventilation group

    Patients with Guillain-Barré Syndrome do not require mechanical ventilation during hospitalization

    Outcome Measures

    Primary Outcome Measures

    1. the severity of Guillain-barre syndrome [baseline, at 1 week, at 26 weeks]

      The Guillain-Barre syndrome disability score is a wide scale for the severity of Guillain-Barre syndrome (0, optimal health; 1, minor symptoms, able to run; 2, able to walk unaided 10 m, unable to run; 3, able to walk 10 m across an open space with help; 4 bedridden or wheelchair users; 5, require assisted ventilation; 6, dead)(deceased).The higher the score, the worse the prognosis.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    N/A and Older
    Sexes Eligible for Study:
    All
    Inclusion Criteria:
    • patients fulfilled clinical, biological, and electrophysiology criteria for Guillain-barre syndrome.
    Exclusion Criteria:
    • nonidiopathic Guillain-barre syndrome and Miller Fisher syndrome

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang China 325000

    Sponsors and Collaborators

    • First Affiliated Hospital of Wenzhou Medical University

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    First Affiliated Hospital of Wenzhou Medical University
    ClinicalTrials.gov Identifier:
    NCT06032741
    Other Study ID Numbers:
    • GBS
    First Posted:
    Sep 13, 2023
    Last Update Posted:
    Sep 13, 2023
    Last Verified:
    Dec 1, 2022
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by First Affiliated Hospital of Wenzhou Medical University
    Guillain-Barre Syndrome
    Additional relevant MeSH terms:
    Guillain-Barre Syndrome
    Syndrome

    Study Results

    No Results Posted as of Sep 13, 2023