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The Prognostic Assessment of Extubation in Aged Patients With Multiple Organ Dysfunction Syndrome

Sponsor
Chinese PLA General Hospital (Other)
Overall Status
Unknown status
CT.gov ID
NCT01802983
Collaborator
(none)
1
Enrollment
1
Location
59
Duration (Months)
0
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The multiple organ dysfunction syndrome (MODS) has remained the major factor contributing to prolongation of intensive and mortality. It is reported that the mortality rates have varied between 20% and 100%, depending on number, severity, duration, type and combination, and definition of dysfunction. In our study, the investigators explore some comprehensive treatment technology to improved outcomes of MODS patients.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    1 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Retrospective
    Official Title:
    Key Technology Research of the Comprehensive Treatment of Multiple Organ Dysfunction Syndrome
    Study Start Date :
    Jan 1, 2009
    Anticipated Primary Completion Date :
    Dec 1, 2013
    Anticipated Study Completion Date :
    Dec 1, 2013

    Outcome Measures

    Primary Outcome Measures

    1. the prognostic assessment of aged patients with MODS [28 days]

      According to the outcomes of 28-day,all the enrolled patients were divided into survival group and death group, clinical datum of which were collected and analysed. And then these prognosis were evaluated with the current scoring systems [(Acute Physiology and Chronic Health EvaluationⅡ(APACHEⅡ, APACHE Ⅲ), Sample Acute Physiological score(SAPSⅡ), Multiple Organ Dysfunction score(MODS)], the predictive power of which were compared by receiver operating characteristic(ROC) curve. Finally, a binary logistic regression analysis was performed to evaluate the concerning prognostic factors of MODSE.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    60 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • age > 60 years old;

    • presence of altered organ function in an acutely ill patient such that homeostasis cannot be maintained without intervention;

    • have trachea intubation after admitting to intensive care unit within 24 hours.

    Exclusion Criteria:
    • end stage multiple organ failure.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Chinese PLA General Hospital Beijing Beijing China 100853

    Sponsors and Collaborators

    • Chinese PLA General Hospital

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Kun Xiao, Key Technology Research of the comprehensive treatment of Multiple organ dysfunction syndrome, Chinese PLA General Hospital
    ClinicalTrials.gov Identifier:
    NCT01802983
    Other Study ID Numbers:
    • 2013670808
    First Posted:
    Mar 4, 2013
    Last Update Posted:
    Mar 4, 2013
    Last Verified:
    Feb 1, 2013
    Keywords provided by Kun Xiao, Key Technology Research of the comprehensive treatment of Multiple organ dysfunction syndrome, Chinese PLA General Hospital
    Aged
    Multiple organ failure
    Extubation
    Prognosis
    MODS
    invasive mechanical ventilation
    Additional relevant MeSH terms:
    Syndrome
    Multiple Organ Failure

    Study Results

    No Results Posted as of Mar 4, 2013