MECATHOR: Prospective Evaluation of the Biomechanical Properties of the Thoracic Aorta Coupling Magnetic Resonance Imaging and In-vitro Elasticity Tests in Patients With Ascending Aortic Aneurysm
Sponsor
Centre Hospitalier Universitaire Dijon (Other)
Overall Status
Recruiting
CT.gov ID
NCT03746964
Collaborator
(none)
200
1
73.5
2.7
Study Details
Study Description
Brief Summary
The biomechanical properties of the aorta are currently poorly understood. A better understanding would optimize surgical indications and monitoring techniques for patients with thoracic aortic aneurysms.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Anticipated Enrollment
:
200 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Prospective Evaluation of the Biomechanical Properties of the Thoracic Aorta Coupling Magnetic Resonance Imaging and In-vitro Elasticity Tests in Patients With Ascending Aortic Aneurysm
Actual Study Start Date
:
Dec 17, 2018
Anticipated Primary Completion Date
:
Dec 1, 2024
Anticipated Study Completion Date
:
Feb 1, 2025
Outcome Measures
Primary Outcome Measures
- aortic compliance by cardiac MRI [Before surgery]
- In-vitro testing of the elasticity of the aortic wall fragment collected during surgery. [through study completion, an average of 12 months]
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
Person who has given oral consent
-
Patient with ascending aortic aneurysm with surgical indication for replacement
-
Age > 18 years old
-
Scheduled surgery
Exclusion Criteria:
-
Person not affiliated to the national health insurance system
-
Protected adult
-
Pregnant or breastfeeding woman
-
MRI Contraindication
-
Emergency surgical procedure
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Chu Dijon Bourogne | Dijon | France | 21000 |
Sponsors and Collaborators
- Centre Hospitalier Universitaire Dijon
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Centre Hospitalier Universitaire Dijon
ClinicalTrials.gov Identifier:
NCT03746964
Other Study ID Numbers:
- MORGANT 2018 MECATHOR
First Posted:
Nov 20, 2018
Last Update Posted:
Dec 10, 2021
Last Verified:
Dec 1, 2021
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: