HPI Effect in Robotic Urological Surgery on AKI
Study Details
Study Description
Brief Summary
It is a single-center randomized controlled trial that aims to figure out the effect of the hypotension prediction index (HPI) on the prevention of acute kidney injury (AKI) after robot-assisted urological surgery. The primary hypothesis is that HPI software guidance prevents postoperative AKI by reducing the duration and severity of intraoperative hypotension (IOH).
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
N/A |
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Experimental: HPI Managing intraoperative hemodynamic condition under the HPI guidance |
Device: BP management with HPI guidance
The hemodynamic condition of the HPI group will be managed by HPI guidance which is derived by arterial pressure waveform information, including Eadyn, SVV, dP/dt.
|
No Intervention: Control Managing intraoperative hemodynamic condition with standard anesthesia care (blinding the HPI monitor screen) |
Outcome Measures
Primary Outcome Measures
- Acute kidney injury [Seven day after the operation]
Occurrence of acute kidney injury after robotic urological surgery
Secondary Outcome Measures
- Depth and duration of hypotension [From applying HPI (hypotension prediction index) monitor to the arterial line to the end of the anesthesia]
Depth and duration of hypotension will be assessed by calculating time weighted average (TWA) of hypotension under mean arterial pressure under 65 mmHg during the operation
- Hypotension prediction index [From applying HPI (hypotension prediction index) monitor to the arterial line to the end of the anesthesia]
Time weighted average of hypotension prediction index during the operation
Eligibility Criteria
Criteria
Inclusion Criteria:
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Age ≧ 19
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Patients undergoing robot-assisted urological surgery
Exclusion Criteria:
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Unable to voluntarily give consent
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Unable to use both radial arteries due to such reasons: prior surgery on the radial artery, breast cancer history with axillary LN dissection, AV fistula for renal replacement therapy, or abnormal Allen's test.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Ewha Womans University Mokdong Hospital | Seoul | Korea, Republic of | 07985 |
Sponsors and Collaborators
- Ewha Womans University Mokdong Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 2023-02-016-003